13 Chicago Companies Redefining Healthtech

Chicago is a nerve center for healthcare technology. Here are the companies to know.

Written by Abel Rodriguez
doctor with computer in healthcare setting
Photo: Shutterstock
UPDATED BY
Abel Rodriguez | Dec 16, 2025
REVIEWED BY
Sara B.T. Thiel | Dec 16, 2025
Summary: Chicago is a nerve center for healthtech, with companies like Tempus AI and GoHealth redefining care. From cancer data analysis to senior living management, these innovators are enhancing access and quality for patients and providers across the industry.

Access to healthcare and the quality of care is a hot topic in Washington these days, but key players in the tech space have been working on these issues for decades. Chicago is a nerve center for health tech and we’ve rounded up the top startups and tech companies working on everything from helping hospitals reduce infections to keeping office dwellers healthier while sitting at their desks.

Top Healthtech Companies in Chicago

  • GoHealth
  • Tempus
  • VillageMD
  • Higi
  • Visibly
  • PhysIQ

Related ResourcesTech & Startup Jobs in Chicago

 

Chicago Healthtech Companies to Know

Founded: 1996

Focus: Healthcare financial analytics

Strata Decision Technology provides cloud-based financial planning, decision support and performance analytics for the healthcare industry. The company helps finance professionals elevate their performance by acquiring insights, accelerating decisions and advancing business plans. Strata has two campuses: its headquarters in downtown Chicago and a second location just outside St. Louis, Missouri.

 

Founded: 2010 

Focus: Healthcare analytics solutions 

Q-Centrix helps health organizations unlock the potential of clinical data with its Enterprise Clinical Data Management platform. The company  leverages expert insights to organize and distribute clinical data across various departments. Instead of investing time and resources in training staff, healthcare teams can rely on the platform to filter immense amounts of clinical data. Q-Centrix enables companies to tailor its flexible technology to meet the needs of professionals in cardiology, oncology, and other areas.

 

Founded: 2013

Focus: Cancer diagnostics and treatment

CancerIQ develops technology that helps healthcare organizations scale cancer prevention, early detection and personalized care. Its platform uses risk models to identify patients and support prevention and early detection strategies. According to the company, its platform helps clinicians incorporate these insights into routine care.

 

Founded: 2005

Focus: Senior living software

Software company Medtelligent specializes in innovative solutions for senior living communities. Its flagship platform, ALIS, or Assisted Living Intelligent Solutions, provides tools that enhance communication, simplify documentation and streamline management processes. ALIS helps assisted living communities eliminate tedious paperwork, empower staff, communicate with families and improve portfolio performance. Medtelligent’s offices are in River North.

 

Founded: 2001

Focus: Insurance marketplace

GoHealth's platform is a beacon in the often  confusing and complicated world of health insurance. Not just for consumers, the company offers solutions for every player in the industry, including carriers and insurance agents. GoHealth has helped over 2 million users find the right coverage while providing the information and insight needed to fully understand their plans.

 

Founded: 2016

Focus: Pharmacy reimbursement software

Kalderos is a healthtech company that uses data analytics to reduce waste and inefficiencies in medical administration. Using extensive data on drug discounts, the company built the first-ever discount management platform for prescription drugs, which helps push the pharma industry toward pricing transparency for patients. 

 

Founded: 2015

Focus: AI precision medicine

Tempus is creating the largest library of clinical and molecular data in the world. Its goal is to ultimately bring cancer treatment into the 21st century with data-driven insights physicians can use to make more effective and personalized treatment decisions. Tempus is working to make each patient experience better than the last and have partnered with a swath of prominent institutions like Mayo Clinic, Northwestern Medicine and Rush University Medical Center.

 

Founded: 1987

Focus: Patient engagement solutions

PatientPoint makes healthtech for doctor’s offices and hospitals, providing health education and doctor-patient communication that’s designed to improve outcomes and patient satisfaction. It works with more than 140,000 medical providers in nearly 40,000 offices. PatientPoint says its products are behind measurable positive healthcare outcomes, such as increases in proactive health services in the form of mammograms and colon cancer screenings.  

 

Founded: 2020

Focus:  Fertility care

Fertility care startup Partum Health focuses on improving outcomes for pregnancy, birth and postpartum care. The company provides families with services such as doula care, mental health integration, nutrition counseling and physical rehabilitation, delivered through a hybrid mix of virtual and in-person care.

 

Founded: 2012

Focus: Digital vision care

Visibly provides digital eye care solutions that expand access to vision testing. Since launching, the company has developed an online visual acuity test that enables patients to complete vision screenings remotely. Licensed eye care professionals then review the results.

 

Founded: 2013

Focus: Primary care platform

VillageMD is a Chicago-based healthcare company transforming how primary care is provided throughout the country. It offers virtual and in-home care as well as provides independent practices with tools and insights to enhance patient care. Its flagship platform combines clinical services and data analytics to support coordinated care, improve health outcomes and help practices negotiate with insurers.

 

Founded: 2022

Focus: Clinical trial research and software

Prolaio is based out of Chicago and offers healthtech software with a mission to drive clinical innovation and enable better patient outcomes. Its platform is designed to help clinicians translate complex clinical data into insights that inform decision-making and treatment strategies for patients. The company says it is rapidly expanding its teams to shape the future of cardiovascular care.

 

Founded: 2012

Focus: Health screening, hardware

Higi is a health station that lets users track their health. Going beyond steps and heart rate, the Higi informs on a variety of health factors like Body Mass Index, pulse, weight, blood pressure and body fat percentages. Higi station checks paint a full portrait of a user’s health, and its mobile app lets them monitor progress from anywhere at anytime. Higi also has a built-in community where users can find friends to follow and groups to join for that extra bit of support.

 

Frequently Asked Questions

Chicago serves as a nerve center for healthtech, where companies have spent decades addressing critical issues ranging from reducing hospital infections to improving employee health in the workplace.

Companies highlighted in the article focus on improving care quality, reducing hospital infections, increasing pricing transparency for prescription drugs, improving clinical decision-making, supporting senior living communities and enhancing doctor-patient communication.

Chicago healthtech companies use a mix of cloud-based software platforms, data analytics, clinical data management systems and digital health tools built to support healthcare providers, patients and administrators.

Ana Gore, Margo Steines and Dana Cassell contributed reporting to this story.

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