Computational Systems Biologist

| Chicago
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Passionate about making a difference in the world of cancer genomics?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

We are seeking an independent and motivated Computational Biologist to join our Computational Systems Biology group. This individual will work in an interdisciplinary team to study transcriptome profiles in cancer using unique and growing collections of genomic data coupled with clinical data. The successful candidate will work in an interdisciplinary team, carry out data analysis, and apply best-in-class algorithms - or develop new algorithms - that directly address important biological and clinical questions.

What You’ll Do

  • Design, develop and execute computational research projects of high complexity.
  • Analyze and integrate large diverse clinical and molecular datasets to extract insights, and drive research opportunities.
  • Evaluate new emerging technologies in healthcare.
  • Develop the next generation of multi-modal products that will change clinical outcomes.
  • Document, summarize and communicate highly technical results and methods clearly to non-technical audiences.
  • Interact cross-functionally with a wide variety of people and teams.

Required Qualifications

  • PhD degree in a quantitative discipline (e.g. statistical genetics, cancer genetics, bioinformatics, computational biology, or similar). Alternately, a PhD in molecular biology combined with a very strong record of high-throughput sequencing data analysis, or equivalent practical experience.
  • Proficient in R, Python, and SQL.
  • Experience developing, training, and evaluating classical machine learning models.
  • Experience with integrative modeling of multi-modal clinical and omics data.
  • Previous experience working with large transcriptome data sets.
  • Thrive in a fast-paced environment and willing to shift priorities seamlessly.
  • Experience with communicating insights and presenting concepts to diverse audiences.
  • Team player mindset and ability to work in an interdisciplinary team.

Preferred Qualifications

  • Strong peer-reviewed publication record.
  • Strong knowledge of cancer or molecular and cell biology. 
  • Significant quantitative training in probability and statistics. Demonstrated willingness to both teach others and learn new techniques.
  • Familiarity with common large transcriptome databases such as TCGA, GTEx, and CCLE.
  • Experience in network analysis and survival analysis.
  • Experience with: tidyverse, ggplot, Git, matplotlib, seaborn, HTML5, CSS3, JavaScript, D3, Plot.ly, Flask, Dask, Docker, AWS.
  • Experience with supervised and unsupervised machine learning algorithms, and ensemble methods, such as: PCA, regression, deep neural networks, decision trees, gradient boosting, generalized linear models, mixed effect models, non-linear low dimensional embeddings and clustering.
  • Experience in agile environments and comfort with quick iterations.
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Technology we use

  • Engineering
  • Product
  • Sales & Marketing
    • JavascriptLanguages
    • PythonLanguages
    • SqlLanguages
    • AWSLanguages
    • ReactLibraries
    • ReduxLibraries
    • Node.jsFrameworks
    • Microsoft SQL ServerDatabases
    • MySQLDatabases
    • PostgreSQLDatabases
    • SQLiteDatabases
    • tableuAnalytics
    • JIRAManagement
    • SalesforceCRM

Location

600 WEST CHICAGO AVENUE, Chicago, IL 60654

An Insider's view of Tempus

What makes someone successful on your team?

We value creativity in ideation, autonomy in execution, and a healthy tendency to always question the status quo.

Ash

Lead Data Scientist

What are Tempus Perks + Benefits

Culture
Volunteer in local community
Friends outside of work
Eat lunch together
Daily stand up
Open door policy
Team owned deliverables
Team based strategic planning
Group brainstorming sessions
Pair programming
Open office floor plan
Health Insurance & Wellness Benefits
Flexible Spending Account (FSA)
Dental Benefits
Vision Benefits
Health Insurance Benefits
Life Insurance
Wellness Programs
Onsite Gym
Retirement & Stock Options Benefits
401(K)
Company Equity
Child Care & Parental Leave Benefits
Generous Parental Leave
Vacation & Time Off Benefits
Unlimited Vacation Policy
Generous PTO
Paid Volunteer Time
Paid Holidays
Perks & Discounts
Beer on Tap
Casual Dress
Commuter Benefits
Company Outings
Stocked Kitchen
Some Meals Provided
Happy Hours
Relocation Assistance
Fitness Subsidies
Professional Development Benefits
Diversity Program
Lunch and learns
Promote from within
Time allotted for learning
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