Sr. Manager, Audience Strategy & Optimization

ROLE SUMMARY
Within Pfizer's Chief Marketing Office, Senior Manager, Audience Strategy and Optimization will be part of the Audience Center of Excellence (CoE), which builds the audience-first ecosystem powering personalized, orchestrated engagement across paid, owned, and earned channels for patients across a multi brand DTC portfolio. The Sr. Manager will support the expansion of digital addressable audiences for the Pfizer BioPharma US business across patient and HCP. As a critical member of the Audience COE, you will participate in the growth and future roadmap for our audience approach and data driven optimizations.
In this role you will partner with Integrated Media Strategy, Analytics, Brand Marketing, Performance Media teams, Measurement and other key CMO commercial teams to ensure the audience strategy is aligned with the marketing objectives and KPI's. The ideal candidate will have a solid background in audience strategy and development, will work well in a matrixed organization, and demonstrate a high level of agility to adapt to changing business needs.
ROLE RESPONSIBILITIES

• Develop strategy and support execution of a comprehensive audience approach across Consumer and HCP brands, providing strategic recommendations, partnership, and education to internal stakeholders on implementing key audience functions and tactics.

• Assist in establishing, developing, and promoting best practices for audience strategy, planning, and execution - driving consistency in standards and processes across creation, execution, measurement, and optimization, and translating individual brand learnings into those standards.

• Develop and maintain the CoE's audience segmentation methodology, profiling and activation standards, translating what's learned on individual brands into playbooks, case studies, and governance practices used across the multi brand portfolio.
• Drive expansion of digital audience usage within your assigned brand set, demonstrating ROI improvements that can inform CoE-wide scaling decisions

• Manage strategic relationships with third-party audience data partners (e.g., Swoop, Crossix, IQVIA). Help to evaluate new audience partners as part of the CoE's test and learn prioritized roadmap.

• Collaborate with Media Measurement Team and Audience Analytics lead to develop performance reporting and optimization recommendations for the assigned scope, and translate results and cross-brand patterns into content for the CoE's monthly and quarterly leadership updates.

• Serve as the primary analytics partner to brand and leadership teams for all things audiences, translating ambiguous business questions into audience solutions and directing the ad hoc analysis needed to answer them.

• Advise senior leadership on audience strategy and measurement, shaping reporting to their needs and turning data into recommendations that drive brand planning and media investment decisions.

• Monitor state and federal health-data privacy regulations affecting audience targeting, maintaining exclusion lists in partnership with Legal/Privacy.

• Evaluate emerging audience, media, and AI-enabled tools and vendors, recommending which merit test-and-learn investment on assigned brands and which should scale CoE-wide.

• Support cross functional team members through knowledge sharing on audience methodology and contribute to CoE problem-solving, with growing visibility to senior stakeholders.

BASIC QUALIFICATIONS

• Bachelor's degree required with 6+ years of experience in digital media, audience strategy, advanced analytics, marketing technology, or digital strategy/buying; Master's degree with 5+ years of experience
• Demonstrated experience working with audience strategy for a brand, category, or client, including presenting recommendations directly to key stakeholders.

• Strong knowledge of the audience data ecosystem: DSPs, DMPs, third-party audience data, and data analytics platforms, with experience negotiating or managing data-partner relationships.

• Experience translating individual brand or campaign learnings into repeatable standards, playbooks, or processes used by a broader team.

• Strong analytical abilities - able to interpret data, identify insights, and make data-driven recommendations for optimization.

• Excellent written and verbal communication skills, with experience developing content for senior leadership updates and explaining performance results and audience recommendations to a range of stakeholders.

• Experience managing relationships with cross-functional and external partners, including agencies, clients, in-house teams, and brand teams.

• Experience working with data & audience partners.

• A strong analytical mindset with the ability to leverage data to inform strategic decisions and optimize campaign performance

• Strong attention to detail and prioritization skills, with a proven ability to operate in a fast-paced, high-pressure environment.

• Proficiency in Microsoft Office Suite, especially Excel and PowerPoint.

PREFERRED QUALIFICATIONS

• 5+ years of agency or client-side experience.

• Pharmaceutical experience, with an understanding of pharma marketing guidelines and restrictions (consumer and HCP).

• Understanding of media measurement norms, evolving landscape, and industry standards.

• Experience with DSP-level audience targeting and 1:1 activation approaches.

• Proficiency in top LLM platforms / exposure to AI-enabled tools for marketing or audience analytics.

Additional Job Information:

• Last day to apply: October 19, 2026
• Work Location Assignment: NYHQ or Collegeville, PA; Hybrid

The annual base salary for this position ranges from $124,400.00 to $207,400.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
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EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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