Lead development, validation, and clinical implementation of molecular assays and NGS workflows for a high-throughput clinical laboratory. Design and analyze R&D studies, create SOPs, qualify reagents and equipment, troubleshoot processes, support automation, and drive workflow improvements. Collaborate across teams, mentor junior scientists, and communicate findings to technical and non-technical stakeholders. The role requires experience in assay development, clinical laboratory operations, molecular biology techniques, and regulated laboratory environments.
Passionate about precision medicine and advancing the healthcare industry?
Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.
We are seeking a Senior Scientist to lead the development and validation of new molecular assays and laboratory processes for deployment in our clinical laboratory.
What You’ll Do
- Lead development of molecular assays and NGS workflows for high-throughput clinical laboratories.
- Design, execute, and analyze R&D studies with scientific rigor and attention to detail.
- Lead assay validation and clinical implementation from study design through launch, including workflow development, SOP creation, and documentation.
- Design and execute qualification and validation studies for reagents, instruments, equipment, and methods to support clinical deployment.
- Interpret data, troubleshoot issues, and drive process improvements.
- Collaborate across cross-functional teams and provide scientific leadership in a matrixed environment.
- Communicate clearly and effectively with technical and non-technical stakeholders.
- Train and mentor junior scientific staff and support implementation of new laboratory workflows.
- Support automation and technology initiatives to improve laboratory workflows.
- Manage multiple priorities and adapt quickly in a fast-paced environment.
- Travel up to 10% as needed.
Qualifications
- Ph.D. with 0 or more years of experience, or Master’s degree with 5+ years of relevant experience in molecular biology, assay development, or a related field.
- Experience in assay development and/or validation required.
- Experience in a clinical laboratory environment required; CAP/CLIA/NYSDOH experience preferred.
- Strong analytical, troubleshooting, and experimental design skills.
- Highly organized, detail-oriented, and committed to quality and accuracy.
- Proven ability to learn quickly and adapt to new processes, technologies, and workflows.
- Strong collaboration skills with the ability to lead across teams.
- Excellent oral and written communication skills.
- Ability to manage competing priorities and deadlines in a dynamic environment.
Preferred Technical Experience
- DNA/RNA extraction and purification methods.
- NGS library preparation, hybrid capture, and sequencing workflows.
- PCR-based techniques, including PCR, qPCR, RT-PCR, and ddPCR.
- Nucleic acid manipulation, quantitation, and analysis.
- Assay troubleshooting, root cause analysis, and workflow optimization.
Highly Desirable
- Experience with liquid biopsy workflows.
- Experience with laboratory automation and liquid handling robotics.
- Experience developing and implementing protocols for CLIA-regulated laboratories.
- Familiarity with LIMS and laboratory data systems.
Pay Range: $95,000 - $120,000 USD
The expected salary range may vary for other locations. Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.
We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
Tempus AI Chicago, Illinois, USA Office
Tempus AI Chicago - Tempus Headquarters & Lab Office
Our Chicago office is located in downtown River North. Right on the river and close to neighborhoods like Fulton Market, Central Business District, Lincoln Park, and Streeterville, it's a lively area with convenient transportation access and is home to many bars, restaurants, and coffee shops.
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