Research Associate at Tempus (Chicago, IL)
Passionate about precision medicine and advancing the healthcare industry?
With the advent of genomic sequencing, we can finally decode and process our genetic makeup. In recent years, we have gained a deeper understanding of the role of gene expression in cancer and other human disease processes. Here at Tempus, we believe the greatest promise for the detection and treatment of cancer lies in the deep understanding of molecular activity for disease initiation, progression, and efficacious treatment based on the discovery of unique biomarkers.
We're on a mission to connect an entire ecosystem to redefine how genomic data is used in clinical settings. We're looking to build a laboratory team who are passionate and focused on developing state of the art techniques for creating, processing and interpreting vast amounts of genomic and molecular data.
What you’ll do:
Develop new assays, including but not limited to STARR-seq and candidate enhancer reporter assays.
Maintain cell culture and organoid models of human disease.
Perform routine testing, quality control, calibration, maintenance and proficiency testing in accordance with current laboratory procedures.
Perform complex molecular-based procedures with a high degree of quality and in accordance with established protocols.
Perform routine molecular biology tasks, including nucleic acid extraction, DNA/RNA quantification and qualification, NGS library preparation, transfection, molecular cloning, agarose and polyacrylamide gel electrophoresis, Western blot analysis, RT-qPCR.
Sterilize laboratory equipment and workspaces as assigned. Maintain consistently high biosafety standards.
Obtain 12 continuing education hours in the field of oncology or molecular biology.
Maintain competency to perform all assigned molecular biology protocols in accordance with CAP, CLIA, NYSDOH regulations.
One of the following educational requirements:
MS in medical technology, clinical laboratory science, chemical, physical or biological science and 2 year pertinent clinical or biomedical laboratory experience with molecular biology
BS in medical technology, clinical laboratory science, chemical, physical or biological science and 3 years of pertinent clinical or biomedical lab experience in molecular biology
Excellent communication skills
Thrives in a fast-paced environment
Ability to work with others to plan and carry out scientific programs and experiments
Self-driven and works well in an interdisciplinary team with minimal direction
Strong desire to build products that will save lives and change the course of cancer
Impeccable attention to detail
Experience with STARR-seq, MPRA, or other gene expression reporter assays
Experience with organoid culture
Experience designing and optimizing new assays
Experience with next-generation sequencing
Work in a CLIA/CAP high-complexity laboratory
Knowledge of LIMS platforms and various computer systems