Top Remote Staff Software Engineer Jobs in Chicago, IL

Lead design and delivery of an AI-assisted, least-privilege access platform for developer experience. Define architecture, partner with security and data teams, build APIs and automation, ensure auditability and compliance, mentor engineers, and drive cross-team alignment and best practices.

The Staff Software Engineer will lead technical projects for the Patient Matching team, focusing on scalable systems and API design. Responsibilities include system architecture, mentoring engineers, and collaborating with various stakeholders to enhance patient experiences in mental healthcare.

As a Staff Software Engineer, you will lead the development of computer vision systems for sidewalk inspection, overseeing model lifecycle, system architecture, and mentoring while improving deployment practices.

Lead design and delivery of major Azure-based data systems and production-grade pipelines. Build semantic models, support BI and ML workloads, drive platform architecture and standards, mentor engineers, and solve performance, reliability, and scalability challenges across Fabric, Synapse, Power BI, and broader Azure services.

Design and build scalable, semantically consistent 360 entity data models and transformation pipelines. Implement cleansing, enrichment, KPIs, scoring, and business rules in SQL and Python/Scala, ensure data quality, lineage, and performance at scale. Use AI coding assistants and SDD to accelerate development, create tests and documentation, and collaborate with domain experts, data scientists, and product teams to deliver trusted, reusable data assets.

The role involves leading application performance improvements across multiple platforms, focusing on measurable metrics and driving engineering standards and workflow optimization, using both hands-on coding and strategic influence.

Act as the technical lead between LQMs and client contracts: diagnose workflows, design and deploy software and infrastructure, wrap scientific logic, integrate agentic systems, and own end-to-end compute and data pipeline deployments to enable scientific delivery.

As a Staff Software Engineer, you will lead technical initiatives for the Core Platform team, focusing on infrastructure and security systems to enhance developer productivity and reliability.

Lead the Payments Team by architecting and maintaining high-performance backend services, addressing complex engineering challenges, and mentoring engineering talent.

As a Senior Staff Engineer, you will lead technical vision and architectural direction for Payments Compliance, ensuring scalable and cohesive compliance systems while partnering with cross-functional teams to navigate regulatory requirements.

The Staff Software Engineer will lead AI integration into software design, develop scalable systems, and mentor other engineers while improving best practices.

The role involves leading the architecture and implementation of hypervisor features, mentoring engineers, and driving technical vision for Lynx's Mosaic platform.

As a Staff Software Engineer, you'll lead the development of AI-driven automations, improving data integration and platform capabilities for cybersecurity teams with over 8 years of experience in complex backend applications and distributed systems.

Lead architecture and delivery of integration domains for an AI-driven SecOps platform. Own roadmaps, design microservice integrations (REST, GraphQL, streaming, LLM APIs), mentor engineers, set technical direction, and champion AI tooling to accelerate development, automation, and reliability.

Own and drive architecture for a major clearing-house domain: backend systems in Go on GCP, data pipelines that ingest and deduplicate unstructured vulnerability reports, customer onboarding and entitlement workflows, enforce observability and production readiness, set engineering standards, and collaborate on interfaces and roadmap planning.

Build and maintain electricity cost modeling REST APIs and DBT data pipelines, translate SME requirements into designs, participate in technical reviews, improve engineering processes, and collaborate across remote squads to deliver energy analytics and battery performance simulations.

Build and maintain electricity cost modeling REST APIs and DBT-driven data pipelines. Translate SME requirements into engineering designs, participate in design reviews, improve engineering practices, and deliver scalable analytics and battery performance simulations to inform DER ROI.

Lead architecture and build platform services for GoDaddy's Internal Developer Platform used by 1,000+ engineers. Design high-scale APIs, infrastructure orchestration, and AI-powered developer tooling. Partner with infrastructure, security, and platform teams. Own production systems (performance, reliability, on-call) and drive technical direction to improve developer productivity across APIs, CLI, and UI.

Design, develop, and maintain production-scale APIs and distributed systems in Golang on Kubernetes. Provide technical leadership, participate in design reviews, write tests and documentation, collaborate cross-functionally, improve developer workflows including AI-assisted tooling, and support on-call operations.

The Security Software Engineer will design and implement security controls for MongoDB Atlas, collaborating across engineering teams and ensuring adherence to high security standards.

Lead design and delivery of enhancements to a next-generation AI agent platform. Own large features and infrastructure, mentor engineers, set technical standards, drive cross-team initiatives, improve reliability and SLOs, and influence product and process decisions to scale systems supporting millions of interactions.

The Staff Software Engineer on the AUE team is responsible for designing and maintaining offensive cybersecurity services, mentoring team members, managing projects, ensuring code quality, and driving technical direction within a collaborative environment.

Build and maintain complex customer-facing features, support other engineers, and take ownership of technical decisions while collaborating with Product and Design teams.

The Staff Software Engineer will focus on quality-driven engineering, automated testing, CI/CD pipelines, AI integration, and mentoring junior engineers while collaborating remotely.

The role involves architecting scalable backend systems and data pipelines, providing technical leadership, and ensuring best practices in software development.