Top Remote Senior Full-Stack Engineer Jobs in Chicago, IL

The Senior Full Stack Engineer will develop backend services in .NET, build frontend applications in React, and optimize databases while managing cloud-native infrastructures.

Lead design and implementation of secure, cloud-first enterprise architectures focused on IAM and Zero Trust. Develop full-stack applications, optimize app/database performance, integrate secure APIs, collaborate with engineering and DevSecOps, assess risks and tradeoffs, drive identity modernization and cloud modernization, and mentor software developers while promoting security and engineering best practices.

Design and implement full-stack applications for GenAI, build developer tooling, collaborate with product teams, and enhance AI agent delivery.

Design and build agent-powered mission consoles, collaborate with stakeholders to improve user workflows, and maintain agentic workflows for mission outcomes.

As a Senior Software Engineer, you will design and build a cutting-edge identity search platform and implement AI systems for defense applications, working closely with cross-functional teams to enhance user workflows and support national security.

Build and maintain core platform features, expand Infisical PKI/SSH/KMS product lines, collaborate with CTO and engineers, communicate with enterprise customers, and prototype AI applications for secrets management.

Responsible for defining and building user experiences across the full stack, leading both frontend and backend architecture, mentoring engineers, and ensuring product scalability.

Design, develop, test, and maintain full-stack applications using Angular, TypeScript, Node.js/NestJS; build and integrate RESTful APIs; support ETL and data processing with Python/PySpark; collaborate in SAFe Agile with architects, QA, and DevOps; maintain CI/CD, documentation, and federal compliance; mentor developers and help modernize large-scale federal health IT systems.

As an Operations Reliability Engineer, design and implement automations to eliminate manual tasks in brokerage operations, focusing on efficiency and reliability while collaborating with cross-functional teams.

As a Senior Full Stack Engineer, you'll design and develop custom Shopify applications, integrate solutions, and collaborate with clients to meet their needs.

As a Senior Fullstack Developer, you will build and maintain moderation and user-safety applications for Bluesky's Trust & Safety team, collaborating with product teams and improving tools based on user feedback.

As a Senior Full Stack Engineer, you'll own major features, build across the stack, influence architecture, and ensure security while working closely with a small team.

As a Senior Full Stack Engineer, you'll build high-performance observability tools, engage with developers, and tackle technical challenges in monitoring applications.

Responsible for leading a team of engineers, supporting product development, identifying technical issues, and ensuring high-quality code delivery in backend systems at scale.

This role involves designing and developing scalable web applications, leading projects, mentoring engineers, and ensuring quality through best practices and collaboration.

As a Senior Full Stack Engineer, you'll design and build cloud-native applications for the payments platform, ensuring reliability and scalability. Collaborate with engineering teams to deliver solutions and maintain production systems.

Build and own data-driven dashboards and backend services for DeFi risk analysis. Develop React frontends, GraphQL APIs, and cloud-native data pipelines. Collaborate with research and protocol teams, mentor junior engineers, drive architectural improvements to the Alert Portal, ensure code quality through testing and reviews, and identify product and technical enhancements.

Ship full‑stack SaaS features and fixes, leverage AI‑agentic development workflows to boost throughput, build internal agent/codegen/test pipelines, validate AI output with tests and reviews, decompose monoliths, and collaborate with product and customers on deployments and incidents.

Build end-to-end features, design intuitive interfaces, manage asynchronous backend jobs, and contribute to open-source efforts, while leading project development from concept to monitoring.

As a Senior Full Stack Developer at Capnexus, you'll design and build a cloud-native subcontractor pre-qualification platform using AWS, incorporating AI and modern frontend/backend technologies, ensuring seamless integration and deployment.

As a Senior Full-Stack Engineer, you will build features across React/TypeScript and Python/Django, shape product outcomes, and collaborate with cross-functional teams to ensure user satisfaction and engineering quality.

Design, build, and maintain scalable web applications using Python and React. Collaborate with teams and ensure application security and performance.

Seeking a Senior Fullstack Engineer with frontend focus in React, TypeScript, and Python. Responsibilities include frontend architecture, API building, and leading frontend standards. Requires 5+ years of experience with strong team collaboration.

The Senior Software Engineer will design, develop, and optimize scalable PHP APIs and web applications, collaborating with product and design teams to support product development and implement best coding practices.

As a Full Stack Engineer at Deepnote, you'll develop and enhance features across the tech stack, support community engagement, and tackle complex engineering challenges.