Top Remote Principal Engineer Jobs in Chicago, IL

As a Senior Principal Engineer, you'll define and drive the technical strategy for customer experience platforms, lead architectural decisions, and mentor engineering teams to enhance customer and agent experiences.

Lead design, build, deployment, and operation of highly resilient, high-throughput configuration and publishing systems. Define long-term architecture and strategy, mentor senior engineers, diagnose and fix performance bottlenecks, and leverage AI tools to improve engineering productivity and platform capabilities.

Technical leader defining architecture and implementation for agentic AI in clinical workflows. Decompose workflows into multi-agent systems, select orchestration tools, drive productionization, partner with product and data science, ensure alignment with reference architecture, and maintain documentation and evaluation practices to deliver clinical value.

As a Principal Engineer - Steam Turbine, you will lead steam turbine engineering activities, mentor junior engineers, and support business development efforts while participating in client meetings and conferences.

Lead semiconductor laser testing and Burn-In operations, focusing on capacity planning, equipment development, and cross-functional collaboration. Oversee die-level optoelectronic testing, manage vendor relationships, and define operational strategies for high-volume manufacturing.

Lead technical vision and architecture for the Integrations & APIs team, contribute backend code, design scalable APIs and event-driven systems, mentor engineers, drive cross-functional execution, and build integrations and platform features for a cybersecurity product.

The Principal Engineer provides technical leadership for engineering productivity, influences platform direction, and improves developer experience through assessment and implementation of solutions across teams.

As a Principal Engineer, you will set the engineering vision, lead technical direction, and drive strategy across enterprise platforms, focusing on developer experience and scalability. Responsibilities include designing solutions, collaborating across teams, establishing engineering standards, and mentoring other engineers, all while ensuring alignment with broader business goals.

The Principal Engineer will architect and develop scalable AI-driven data platforms, mentoring engineers and aligning technical strategies with business goals.

Lead technical direction with the CTO, architect and build high-scale distributed systems, mentor engineers, ship product roadmap, manage cloud infrastructure and orchestration, enforce CI/CD, testing and fault-tolerance, and collaborate with product and business teams while leveraging AI/ML frameworks.

The Principal AI/ML Engineer will develop machine learning models for campaign optimization in AdTech, collaborating across engineering and product teams to enhance advertising capabilities.

The Principal Cloud Support Engineer at Wasabi leads technical support, mentors engineers, resolves complex issues, and advises enterprise clients, focusing on cloud storage solutions.

Architect and validate technical solutions for major enterprise accounts, lead the technical sales process, run end-to-end Proofs of Value, and collaborate with internal teams to resolve critical customer security challenges.

Hands-on technical leader who designs, builds, and deploys production-grade AI automation and agentic workflows. Responsibilities include rapid prototyping, RAG and document-intelligence systems, API integrations, orchestration, monitoring, reusable AI assets, and mentoring a small engineering team to deliver frequent releases and measurable business impact.

Lead the machine learning strategy, design scalable ML systems, drive MLOps, mentor engineers, and comply with AI governance.

Senior individual contributor owning system integration and operational readiness for fiber and wireless product launches. Leads ORT, defines end-to-end BSS/OSS integrations, drives automation and vendor coordination, presents business cases to leadership, and ensures scalable subscriber transitions and platform migrations.

Lead design and build of scalable backend systems and data platforms; own architecture and production deployments; improve reliability, performance, and observability; mentor engineers and collaborate with Product, Data Science, SRE, and Security.

Lead end-to-end technical strategy and modernization of iHerb's product catalog platform. Define architecture, data models, APIs, and service boundaries; write production code; drive cross-team technical decisions, mentorship, and AI-driven SDLC standards. Coordinate multi-team efforts, ensure engineering quality, and represent engineering across product, data science, security, and infrastructure.

Own and drive the end-to-end mobile platform architecture for iOS and Android, lead a mobile modernization effort, write production mobile code and prototypes, set technical standards, evaluate cross-platform frameworks, mentor senior engineers, coordinate multi-team architecture reviews, and integrate AI-driven SDLC practices across the engineering organization.

Lead end-to-end technical strategy and implementation for iHerb's AI Platform and GenAI products. Design and build shared AI infrastructure (RAG pipelines, vector search, embeddings, evals, MLOps), set architecture and quality standards, deliver production AI systems, coordinate cross-team technical efforts, and mentor senior engineers.

Lead architecture and hands-on implementation of cloud-native, distributed, high-throughput data systems. Define organization-wide standards for scalability, reliability, security, and observability. Drive transition from batch to streaming-first pipelines, influence executive product/platform decisions, mentor teams, and establish AI-assisted and agentic engineering best practices and guardrails while owning systems end-to-end.

As a Principal Data Engineer, you will design and implement LLM, AI-powered security data platforms, mentor engineers, and drive the adoption of data solutions across teams.

Lead architecture and technical direction for an AI-first SaaS product (Growth Studio). Define scalable services, APIs, data flows, and AI-enabled workflows; guide integrations, run architecture/code reviews and POCs; mentor engineers; produce technical documentation; and partner with product, UX, QA, and ops to deliver reliable, secure, and maintainable platform capabilities for GovCon customers.

Hands-on technical leader and core individual contributor building cloud-native defense/intelligence software. Drive architecture, code reviews, feature delivery, and mentor a small Agile team while implementing DevOps, CI/CD, and robust AWS/EKS-based deployments.

Design and architect cloud-first, full-stack, scalable SaaS products; provide technical leadership, mentor engineers, promote automated testing and CI/CD, integrate AI/ML features (LLM/RAG), ensure observability and security, and collaborate with product, operations, and support.