Top Remote Senior Program Manager Jobs in Chicago, IL

Lead end-to-end program management for partner experience platforms: define roadmap, partner with engineering on architecture and delivery, drive cross-functional alignment, measure outcomes via telemetry and KPIs, manage vendors/SOWs, ensure compliance (privacy, accessibility, security), and apply AI and data to prioritize investments and improve partner experiences at scale.

Lead and manage midsize-to-large regulatory affairs outsourcing programs, advising clients, driving project delivery and profitability, supporting business development and proposals, mentoring project teams, and staying current with regulatory and industry trends to deliver tailored solutions.

Lead operational execution for Product & Engineering: drive day-to-day SDLC, manage work from triage to completion, maintain GitHub Projects as source of truth, coordinate cross-functional teams, remove blockers, and improve engineering processes and delivery predictability.

Lead end-to-end technical programs for ML infrastructure (inference, serving, efficiency, endpoints). Coordinate cross-functional teams, prioritize overlapping projects, manage timelines, budgets and scope, drive incident management and continuous improvement, and communicate status to engineering and leadership.

Lead health screening and clinical research programs from planning through delivery. Manage multiple projects, timelines, regulatory adherence, interdisciplinary collaboration, program performance, reporting, participant concerns, and continuous improvement. Mentor a senior analyst and guide program teams while applying clinical research methodology and strategic operational leadership.

Lead enterprise CRM and Salesforce transformation programs from strategy through delivery. Own scope, governance, roadmaps, budgets, risks, vendors, integrations, platform modernization, adoption, and business outcomes across multiple Salesforce clouds. Partner with executive sponsors and cross-functional global teams spanning technology, product, sales, marketing, customer success, data, and operations. Drive CRM analytics, automation, AI-enabled capabilities, customer data initiatives, and governance using Agile, Waterfall, or hybrid delivery methods.

Lead the creation and management of the enterprise program management infrastructure, enhance cross-functional collaboration, and drive successful strategic initiative delivery using AI and automated systems.

Pipeline for program management roles at multiple seniority levels. Responsibilities include program planning, scheduling, budgeting, risk management, milestone tracking, stakeholder communication, vendor coordination, and leading programs from concept through launch. Candidates should have PM tool experience and strong cross-functional leadership. Submit a resume to join the talent network.

Manage multiple concurrent data-center infrastructure projects including requirements gathering, scope and technical documentation, vendor/sole-source management, commissioning coordination, procurement support, risk and schedule tracking, and driving LFP (Lithium Ion) conversions for APC Symmetra MW UPS battery systems while ensuring operational readiness and safety in active construction environments.

Lead cross-organization technical programs for Azure Specialized Compute, supporting customer cloud migrations and high-performance/GPU workloads. Drive end-to-end initiatives, mentor junior team members, and coordinate with product and engineering teams to deliver scalable compute services.

Lead complex Azure Storage initiatives for strategic AI and data analytics customers. Provide Blob Storage architectural guidance for HPC and machine learning workloads, manage cross-functional technology programs, influence technical priorities through customer feedback, mitigate risks, and improve operational efficiency. The role requires technical depth in cloud infrastructure, high-scale systems, resiliency, performance, capacity management, and production operations, along with strong stakeholder influence.

Manage and launch innovative learning programs globally, enhance user adoption, and leverage AI and data for effective enablement.

Leads end-to-end content initiatives supporting customer experience and thought leadership programs. Manages planning, prioritization, timelines, dependencies, approvals, vendors, content lifecycle execution, stakeholder collaboration, reporting, and performance insights. Partners with communications, marketing, product, legal, leadership, writers, designers, and agencies to deliver high-quality, brand-aligned content across channels.

Leads complex technical programs transforming data center delivery across engineering, construction, networking, finance, and operations. Drives schedules, budgets, quality, KPIs, reporting, process improvement, automation, and cross-functional decision-making. Applies technical knowledge of data center systems and infrastructure while managing ambiguity, executive stakeholders, pilots, and large-scale initiatives across Microsoft’s cloud organization.

Leads complex design programs for premium live sports and entertainment broadcasts, managing graphics packages, studio design systems, production schedules, budgets, vendors, and technical playout workflows. Partners with creative, engineering, production, and executive stakeholders while overseeing on-site graphics integration from remote production trucks. Requires deep broadcast operations expertise, strong leadership, and extensive domestic and international travel for year-round live events.

Lead delivery of complex AI-native security programs, operationalize AI/LLM deployments, manage risks and dependencies across engineering and SecOps, define governance and best practices, and translate technical strategy for executives to meet product milestones.

Lead cross-functional transformation programs by maintaining governance, driving execution, managing risks and dependencies, and producing executive reporting to ensure alignment, adoption, and delivery of strategic objectives.

Own end-to-end operating model and outcomes for provider engagement and growth programs. Lead cross-functional teams, track and report program performance from CRM and other data sources, surface and escalate risks, engage directly with practices/providers as needed, and design scalable playbooks and operating processes.

The Sr Program Manager will lead cross-functional teams on complex insurance transformation projects, ensuring delivery on scope, schedule, and budget while optimizing business processes and modernizing enterprise systems.

Lead and coordinate cross-functional engineering projects embedded with customers, define success criteria, drive roadmaps and governance, validate use cases and test plans, collect performance metrics, and manage direct customer engagements to deliver cloud and AI-based solutions.

Lead a pharmacy accounts and sales support team to drive membership growth and retention. Partner with sales, underwriting, and business units to develop pharmacy strategies, RFP responses, pricing approaches, client renewals, training materials, and sales collateral. Manage client issues, ensure contract deliverables, and present pharmacy value to clients, brokers, and consultants.

Lead and deliver multiple concurrent engineering programs by defining objectives, success metrics, and milestones; facilitate PI planning; identify and resolve risks; build program management processes and tooling from scratch; use AI tools to automate workflows; communicate progress and impacts to senior leadership and stakeholders to ensure reliable delivery.

Lead procurement strategy and supplier selection for inbound products and services. Manage RFIs/RFPs, negotiate contracts with Legal, administer Coupa purchase orders, reconcile invoices, and apply AI/ML and reporting tools to optimize procurement processes while collaborating with cross-functional senior stakeholders.

Lead and deliver complex, cross-team AI platform programs: manage schedules, risks, integration of AI workflows and agents, enable operational readiness, drive TPM best practices, and communicate status and metrics to stakeholders in a remote, multi-timezone environment.

Lead and execute strategic revenue programs and events for the CRO organization, including executive briefing and sponsorship programs, investor relations, SKO and incentive trip logistics, CRO operating rhythm and QBR coordination, and employee recognition/gifting. Manage vendor coordination, registration websites, budgets, procurement, and cross-functional stakeholders to drive revenue and retention.