Top Senior Program Manager Jobs in Chicago, IL

Drive complex, cross-functional engineering projects as a Product Owner: define customer scenarios, coordinate engineering and stakeholders, deliver roadmaps, track schedules, validate use cases, write test cases, collect metrics, lead governance and customer engagements to implement cloud and AI-based solutions.

Serve as senior acquisition lead providing cradle-to-grave federal acquisition support: acquisition planning, solicitation development, evaluation, awards, post-award administration, reporting, quality control, and coordination with Contracting Officers, CORs, program offices, and contractors. Manage contractor acquisition staff, track PALT and procurement metrics, prepare status reports, ensure FAR/HHSAR compliance, maintain auditable electronic contract files, and use CDC procurement systems (ICE, FPDS, SAM.gov). Ensure information security, records management, and agency access requirements are met.

Lead end-to-end technical programs across multiple teams using Azure DevOps and Portfolio++. Define roadmaps, manage dependencies, run Agile ceremonies, surface and resolve risks, build PMO practices, and deliver executive-ready status and dashboards to ensure predictable, outcome-driven delivery.

Lead and execute cross-functional technical programs: plan engineering work, manage dependencies and risks, communicate status to stakeholders, support product and engineering teams, manage backlogs, and build consensus to deliver roadmap objectives.

Operate as the GM of Games' right hand: run division operating rhythm, manage GM calendar and meetings, aggregate cross-functional status and risks, track decisions and actions, produce executive briefing materials, and lead division-wide operating projects and process improvements.

Lead and grow Microsoft Security's compliance program by monitoring regulations, assessing applicability, aligning stakeholders, and coordinating implementations. Provide guidance on policy, risk management, incident response, and training. Build measurement frameworks and maturity models, stay current on regulatory changes, and advise senior leadership on compliance strategy.

Lead new-client implementations of a digital banking SaaS platform, managing program schedules, risks, budgets, and cross-functional coordination. Serve as primary customer contact, track tickets/backlogs, validate configurations, report status to stakeholders, and drive process improvements and team mentoring to ensure successful launches and customer satisfaction.

Lead cross-organization technical programs for Azure Specialized Compute, supporting customer cloud migrations and high-performance/GPU workloads. Drive end-to-end initiatives, mentor junior team members, and coordinate with product and engineering teams to deliver scalable compute services.

The Senior Program Manager oversees complex IT contracts for DoD, managing projects, teams, and stakeholder communications while ensuring quality and compliance.

Lead cross-organizational capacity management programs for Microsoft Entra services. Develop and execute capacity planning strategies, forecast demand, secure supply, track deployment readiness, mitigate risks, optimize infrastructure efficiency at hyperscale, drive data-driven decisions, influence stakeholders, and implement automation and process improvements to meet service-level commitments.

Lead operational execution of the information security program: coordinate cross-functional initiatives, track roadmap and audit evidence, build metrics and executive dashboards, manage policy and awareness programs, and handle vendor/MSSP administration to ensure audit readiness and regulatory compliance.

Own end-to-end operating model and outcomes for provider engagement and growth programs. Lead cross-functional teams, track and report program performance from CRM and other data sources, surface and escalate risks, engage directly with practices/providers as needed, and design scalable playbooks and operating processes.

Lead cross-team technical programs for Azure Storage: define roadmaps, coordinate execution, design technical solutions, identify risks and mitigations, validate use cases and tests, collect metrics, and drive customer and stakeholder engagement.

Lead and mentor TPMs to deliver AI platform initiatives across search relevance, recommendation systems, and ML infrastructure. Align stakeholders, define measurable success criteria, manage risks and dependencies, drive execution, and present outcomes to senior leadership. Partner with ML, infrastructure, and product teams to shape technical direction and accelerate data-driven AI initiatives.

Lead deep technical engagement with large enterprise customers to drive platform reliability and performance improvements. Own planning and delivery of complex cross-team technical programs, manage escalations, translate recurring customer issues into engineering actions, and communicate program status. Collaborate with product, engineering, support, and field teams to define success metrics and ensure measurable platform improvements for mission-critical workloads.

Lead and deliver complex, cross-team AI platform programs: manage schedules, risks, integration of AI workflows and agents, enable operational readiness, drive TPM best practices, and communicate status and metrics to stakeholders in a remote, multi-timezone environment.

Lead and deliver multiple concurrent engineering programs by defining objectives, success metrics, and milestones; facilitate PI planning; identify and resolve risks; build program management processes and tooling from scratch; use AI tools to automate workflows; communicate progress and impacts to senior leadership and stakeholders to ensure reliable delivery.

Lead a pharmacy accounts and sales support team to drive membership growth and retention. Partner with sales, underwriting, and business units to develop pharmacy strategies, RFP responses, pricing approaches, client renewals, training materials, and sales collateral. Manage client issues, ensure contract deliverables, and present pharmacy value to clients, brokers, and consultants.

Lead procurement strategy and supplier selection for inbound products and services. Manage RFIs/RFPs, negotiate contracts with Legal, administer Coupa purchase orders, reconcile invoices, and apply AI/ML and reporting tools to optimize procurement processes while collaborating with cross-functional senior stakeholders.

Lead and execute strategic revenue programs and events for the CRO organization, including executive briefing and sponsorship programs, investor relations, SKO and incentive trip logistics, CRO operating rhythm and QBR coordination, and employee recognition/gifting. Manage vendor coordination, registration websites, budgets, procurement, and cross-functional stakeholders to drive revenue and retention.

Own end-to-end authentication and campaign setup/management UI, translate product strategy into executable roadmaps, drive squad delivery, align stakeholders, use data to prioritize, and partner with engineering to manage technical sequencing and risk for high-traffic, revenue-critical advertiser flows.

Lead end-to-end program management for partner experience platforms: define roadmap, partner with engineering on architecture and delivery, drive cross-functional alignment, measure outcomes via telemetry and KPIs, manage vendors/SOWs, ensure compliance (privacy, accessibility, security), and apply AI and data to prioritize investments and improve partner experiences at scale.

Lead end-to-end delivery of strategic IT programs, define integrated program plans, manage risks and dependencies, align stakeholders and report to executive sponsors, and drive PMO process improvements.

Manage and launch innovative learning programs globally, enhance user adoption, and leverage AI and data for effective enablement.

Lead end-to-end technical programs for ML infrastructure (inference, serving, efficiency, endpoints). Coordinate cross-functional teams, prioritize overlapping projects, manage timelines, budgets and scope, drive incident management and continuous improvement, and communicate status to engineering and leadership.