Top Python Jobs in Chicago, IL

9 Days AgoSaved
In-Office
Chicago, IL
Senior level
Senior level
Information Technology • Professional Services • Consulting • Financial Services
Develop and maintain Python-based applications, collaborate with cross-functional teams, write clean efficient code, debug and optimize performance, participate in code reviews, and follow development best practices.
Top Skills: CSSDjangoFlaskGitHTMLJavaScriptPython
Reposted YesterdaySaved
Remote
Chicago, IL
Mid level
Mid level
Agency • Artificial Intelligence • Blockchain • Web3
Build and maintain API services for a decentralized exchange, design and implement trade routing logic for optimized cross-chain swaps, integrate features with cross-functional teams, monitor system performance and reliability, and troubleshoot trade execution and API issues.
Top Skills: Node.jsPythonRedisSQL
Reposted YesterdaySaved
Remote
Chicago, IL
139K-203K Annually
Senior level
139K-203K Annually
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Marketing Tech • Software • Biotech • Design
Develop and maintain backend solutions, ensuring performance, security, and regulatory compliance, while collaborating in cross-functional teams.
Top Skills: AWSFastapiPython
Reposted 3 Days AgoSaved
Remote
Chicago, IL
Senior level
Senior level
Information Technology • Consulting
Design and build applications using Python, manage component design, optimize performance, and collaborate with clients on innovative products.
Top Skills: Ai ToolsCi/CdGitGoKubernetesPythonReact
Reposted 4 Days AgoSaved
Remote
Chicago, IL
Mid level
Mid level
Artificial Intelligence • Computer Vision • Machine Learning • Software
Build and maintain Django-based web applications, design RESTful APIs, implement frontend features (HTML/CSS/JS), optimize performance and security, collaborate with cross-functional teams throughout the development lifecycle.
Top Skills: CSSDjangoGitHTMLJavaScriptMySQLPostgresPythonRestful Apis
Reposted 5 Days AgoSaved
In-Office or Remote
Chicago, IL
150K-200K Annually
Mid level
150K-200K Annually
Mid level
Artificial Intelligence • Food • Software • Hospitality
Build and maintain Python backend services and serverless architectures for a restaurant operations platform. Ship end-to-end features, design robust systems, and help define product roadmap. Implement CI/CD and productionization, collaborate with product and GTM teams, and contribute to team culture and technical execution.
Top Skills: Aws LambdaAws ServerlessAws Step FunctionsCi/CdGoJavaJavaScriptPythonReactTypescript
5 Days AgoSaved
Remote
Chicago, IL
70-110 Hourly
Junior
70-110 Hourly
Junior
Artificial Intelligence • HR Tech • Professional Services • Software
Design and evaluate performance engineering tasks for AI training/evaluation. Optimize runtime, compilers, memory, CPU/GPU and concurrency. Produce documented solutions, evaluate AI-generated code, and build evaluation frameworks and scoring rubrics while collaborating with researchers and SMEs.
Top Skills: Ai InfrastructureBenchmarking ToolsC++CompilersConcurrencyCpu PerformanceDistributed SystemsGpu PerformanceHigh-Performance ComputingParallel ProcessingPerformance ProfilingPythonRust
Reposted 5 Days AgoSaved
In-Office or Remote
Chicago, IL
Mid level
Mid level
Cloud • Software
We are seeking a software engineer to build and validate resilient distributed systems, enhance CI pipelines, and improve testing strategies for cloud applications.
Top Skills: AWSCircleCIGithub CiGoJenkinsKubernetesOpenstackPythonTerraform
Reposted 5 Days AgoSaved
In-Office or Remote
Chicago, IL
135K-155K Annually
Senior level
135K-155K Annually
Senior level
Machine Learning • Other
The Backend Software Engineer will develop and maintain backend systems for data processing related to coffee farming, utilizing Python and PostgreSQL. Responsibilities include feature development, problem-solving, and adapting systems to regulatory changes while ensuring system resilience.
Top Skills: AWSCi/CdDockerPostgresPostgresql/PostgisPythonTerraform
6 Days AgoSaved
Remote
Chicago, IL
Senior level
Senior level
Artificial Intelligence • Cloud • Information Technology • Consulting
Build and maintain scalable backend services in Python and Java (Spring Boot), develop responsive React frontends, integrate AI/GenAI (LLMs, RAG) using frameworks like LangChain/LlamaIndex, collaborate with cross-functional teams, troubleshoot and optimize systems, and ensure coding, security, and performance best practices.
Top Skills: AWSAzureCi/CdDevOpsGCPGenaiJavaLangchainLlamaindexLlmsNoSQLPythonRagReactSpring BootSQL
6 Days AgoSaved
Remote or Hybrid
Chicago, IL
Senior level
Senior level
Aerospace • Artificial Intelligence • Defense • Manufacturing
Develop and maintain flight and ground station software for satellite communications subsystems. Design and validate constrained-hardware platform applications, improve test coverage and documentation, contribute to architecture and peer reviews, and provide expert support to satellite operations.
Top Skills: BashCi/CdDockerGitGitlabGnu/LinuxHTTPKubernetesPythonTcp/Ip
Reposted 7 Days AgoSaved
Remote
Chicago, IL
Senior level
Senior level
Healthtech • Software
Lead backend development on the scheduling platform modernization, contribute across products, write APIs, and drive AI-accelerated software development workflows.
Top Skills: .NetAgent OrchestrationAi-Assisted DevelopmentLlm ToolingPython
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Senior level
Gaming • Software
As a Senior Full Stack Software Engineer, you will design and maintain the core platform for sports betting, developing APIs and frontend features, optimizing performance, and ensuring compliance while mentoring junior engineers.
Top Skills: Next.JsPythonReactTypescript
Reposted 7 Days AgoSaved
Remote
Chicago, IL
Senior level
Senior level
Healthtech • Software
Lead backend development on the scheduling platform modernization. Contribute across Python and .NET ecosystems, write APIs, review code, and support AI-accelerated development workflows while collaborating in a remote team environment.
Top Skills: .NetAi-Assisted Development WorkflowsClaude CodeLlm ToolingMulti-Agent SystemsPython
Reposted 7 Days AgoSaved
Remote
Chicago, IL
Senior level
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Software • Analytics • Consulting • Financial Services
Lead Software Engineer responsible for designing, developing, testing, and maintaining a distributed processing application using Python and Java. Collaborate with product owners, data coaches, analysts, DBAs, and Agile teams to meet backend/frontend requirements, implement cloud and big-data solutions (Spark/Hadoop), and ensure program standards and reliable delivery.
Top Skills: SparkAWSDroolsHadoopIbm OdmJavaLinuxPythonShell ScriptingSnowflakeSQLVisual StudioVs Code
Reposted 7 Days AgoSaved
Remote
Chicago, IL
Senior level
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Software • Analytics • Consulting • Financial Services
Develop, test, and maintain a complex distributed processing application using Python and Java. Collaborate with product owners, data coaches, analysts, DBAs, and Agile teams to meet backend/frontend requirements. Work with distributed workloads (Spark/Hadoop), SQL/Snowflake, AWS, shell scripting, and job scheduling/process automation. Support delivery under Agile/SAFe practices and ensure alignment with program standards.
Top Skills: AWSBash/Shell ScriptingDroolsHadoopJavaLinux (Cli)OdmPythonSnowflakeSparkSQLVs Code
Reposted 7 Days AgoSaved
Remote
Chicago, IL
4K-5K Hourly
Senior level
4K-5K Hourly
Senior level
Travel
Lead development of Python-based web applications using Django and FastAPI, architect scalable solutions, and establish technical standards while mentoring developers and optimizing infrastructure.
Top Skills: Ai Coding AssistantsAWSDjangoFastapiGitPostgresPythonRailway
Reposted 7 Days AgoSaved
In-Office or Remote
Chicago, IL
2K-2K Annually
Mid level
2K-2K Annually
Mid level
Cloud • Software
As a Python and Kubernetes Software Engineer, you will develop data analytics solutions using open source tools, collaborating with a distributed team.
Top Skills: AirflowApache SupersetApache TrinoAWSAzureClickhouseDbtDockerDvcFeastGCPKubernetesLxdMlflowPythonTemporal
Reposted 7 Days AgoSaved
Remote
Chicago, IL
100K-130K Annually
Mid level
100K-130K Annually
Mid level
Digital Media
The Senior Software Engineer will develop features, maintain quality, review code, and collaborate on product design for the EnrollWise platform, focusing on back-end and some front-end work.
Top Skills: AWSDjangoJavaScriptPython
Reposted 7 Days AgoSaved
In-Office or Remote
Chicago, IL
Senior level
Senior level
Digital Media
Develop and enhance features for EnrollWise, contribute to a scalable software architecture, review code, collaborate on design and technical feasibility, and maintain software quality.
Top Skills: ApolloAWSDjangoDjango OrmGraphQLNextjsPythonReact
One Month AgoSaved
In-Office or Remote
Chicago, IL
Entry level
Entry level
Gaming • Mobile • Travel
Build and maintain Python tools for web scraping, automation, integrations (Airbnb, marketplaces), ad automation, chatbots (Chatwoot), workflow automation (Spiffworkflow), automated tests, and data analysis.
Top Skills: BpmnChatwootClaude CodeCursorDjangoFlaskGitGitlabLinuxNoSQLPytestPythonRequestsSeleniumSpiffworkflowSQLUnittestVs Code Copilot
Reposted 8 Days AgoSaved
Remote
Chicago, IL
156K-205K Annually
Senior level
156K-205K Annually
Senior level
eCommerce
Lead design, build, and operate scalable backend services and carrier integrations. Provide technical leadership, mentor engineers, drive architecture and best practices, write and test code, troubleshoot production incidents, and improve monitoring and reliability while collaborating with product and cross-functional teams.
Top Skills: AWSConfluenceDistributed SystemsEnd-To-End TestingIntegration TestingJIRAMicroservicesMonitoring/Observability/AlertingPythonRelational DatabasesRest ApisSQLUnit TestingVersion Control
10 Days AgoSaved
Remote
Chicago, IL
388K-619K Annually
Senior level
388K-619K Annually
Senior level
News + Entertainment
Build and maintain internal Python platform libraries and tooling to improve developer experience. Drive runtime, dependency, testing, delivery, monitoring, and performance optimization for Python services (including GPU-enabled workloads). Collaborate cross-functionally to define an opinionated SDLC, support on-call rotations, and balance modern practices with risk-aware change. Enable scalable, low-latency distributed systems and provide AI/ML-facing platform capabilities.
Top Skills: CudaDynamoFastapiFlaskLitserveOnnxPythonPytorch (Torch.Compile)Ray ServeTensorrtTritonVllm
Reposted 10 Days AgoSaved
Remote
Chicago, IL
Mid level
Mid level
Information Technology • Professional Services
Seeking a Full Stack Engineer to develop and scale the platform using React and Python. Responsibilities include building frontend applications, developing APIs, managing workflows, and optimizing databases.
Top Skills: Ci/CdDockerGCPPlaywrightPostgresPythonReactTailwindTemporalTypescriptVitest
11 Days AgoSaved
Remote
Chicago, IL
120K-160K Annually
Senior level
120K-160K Annually
Senior level
Artificial Intelligence • Big Data • Cloud • Information Technology • Machine Learning
Design and build full-stack applications that expose AI/ML insights. Develop backend services in Python, RESTful APIs, and containerized microservices. Build high-performance front-end interfaces with React/Vue/Angular. Implement cloud-native solutions on Google Cloud or Azure, manage relational and NoSQL databases, apply testing and CI/CD, and participate in Agile development and architecture sessions.
Top Skills: AngularAzureCi/CdDockerGCPJavaScriptKubernetesMongoDBMySQLPostgresPythonReactRestful ApisSQL ServerTypescriptVue
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