Get the job you really want.

Top Principal Data Scientist Jobs in Chicago, IL

Reposted 9 Days AgoSaved
In-Office or Remote
Chicago, IL
160K-190K Annually
Senior level
160K-190K Annually
Senior level
Digital Media • Fintech • Information Technology • Machine Learning • Financial Services • Cybersecurity • Automation
The Principal Data Scientist will optimize marketing investments through advanced decision support systems, collaborating with multiple business stakeholders, and leading the development of analytics frameworks.
Top Skills: ConoptCplexGamsPyomoPythonScipScipy
Reposted 3 Days AgoSaved
Hybrid
Chicago, IL
147K-185K Annually
Mid level
147K-185K Annually
Mid level
Fintech • Machine Learning • Payments • Software • Financial Services
The role involves developing and deploying machine learning models for anti-money laundering, leveraging advanced analytics, statistics, and large datasets while collaborating with cross-functional teams.
Top Skills: AWSCondaH2OPythonSparkSQL
Reposted 4 Hours AgoSaved
In-Office or Remote
Chicago, IL
132K-178K Annually
Senior level
132K-178K Annually
Senior level
Software
Develop and maintain predictive models for quality, risk adjustment, and operational efficiency; analyze multi-source healthcare data; implement ML solutions, monitor model performance, and experiment with emerging AI to improve outcomes and workflows.
Top Skills: Deep LearningEtl PipelinesFeature StoresFoundation ModelsGenerative AiGitGitLlmsMachine LearningModel RegistriesPythonRest ApisSQL
Reposted 8 Days AgoSaved
Hybrid
Chicago, IL
147K-201K Annually
Senior level
147K-201K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
The role involves leveraging advanced machine learning techniques to analyze cash flow and transaction data, developing predictive models, and collaborating with a cross-functional team to drive customer-focused solutions.
Top Skills: AWSCondaH2OPythonSpark
Reposted 5 Hours AgoSaved
Remote
Chicago, IL
Senior level
Senior level
Artificial Intelligence • Big Data • Information Technology
Design, build, and deploy end-to-end production ML systems for audience targeting, lookalike generation, and propensity scoring. Own ML lifecycle from experimentation to production monitoring, leverage distributed/cloud platforms, implement vector similarity and embedding systems, engineer scalable features, and collaborate with engineering and product teams to ensure model quality and operational reliability.
Top Skills: Aws S3Ci/CdDatabricksFaissGitPythonSnowflakeSparkSQL
Reposted YesterdaySaved
Remote
Chicago, IL
215K-260K Annually
Senior level
215K-260K Annually
Senior level
Security • Software
Lead Data Scientist responsible for creating ML-driven risk assessments and AI workflows within a SaaS security platform, ensuring effective decision-making and system reliability.
Top Skills: AIMachine LearningStatistical Modeling
2 Days AgoSaved
Remote
Chicago, IL
Expert/Leader
Expert/Leader
Other
The Principal Data Scientist will develop fraud detection systems, lead technical projects, mentor team members, and collaborate with engineering to improve data verification processes.
Top Skills: AWSElasticsearchKubernetesLabelboxMongoDBNoSQLPythonRScalaSQLVertexai
Reposted 13 Days AgoSaved
In-Office
Chicago, IL
122K-228K Annually
Senior level
122K-228K Annually
Senior level
Financial Services
The Principal Data Scientist develops predictive models, designs large-scale data pipelines, and collaborates to enhance data-driven decision-making using advanced analytical algorithms.
Top Skills: Artificial IntelligenceAWSAzureDeep LearningGenaiLlmLstmMachine LearningMlopsPower BIPyTorchTensorFlowXgboosting
25 Days AgoSaved
Hybrid
Chicago, IL
147K-185K Annually
Senior level
147K-185K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
As a Principal Associate, Data Scientist, you will develop machine learning models and analytics to combat money laundering, collaborating with a cross-functional team and modernizing risk management practices.
Top Skills: AWSDbtPythonSparkSQL
15 Days AgoSaved
Remote
Chicago, IL
Mid level
Mid level
Healthtech
The Principal Data Scientist develops and deploys machine learning models for operational and clinical uses, performs analyses, and collaborates with various stakeholders.
Top Skills: AzureDatabricksPysparkPythonSQL
Reposted 24 Days AgoSaved
In-Office
Chicago, IL
173K-311K Annually
Expert/Leader
173K-311K Annually
Expert/Leader
Fintech
Lead design, development, and maintenance of fraud-risk and predictive models, architect ETL and storage for large datasets, manage analytic projects and teams, document solutions, research new techniques, and communicate technical results to stakeholders.
Top Skills: Aws SagemakerHivePandasPysparkScalaScikit-LearnSQL
New

Track Smarter, Apply Better.

Ditch the spreadsheets. Organize your job search with our freeApplication Tracker.

Use For Free
Application Tracker Preview
Reposted 15 Days AgoSaved
Remote
Chicago, IL
169K-285K Annually
Expert/Leader
169K-285K Annually
Expert/Leader
Other • Real Estate • PropTech
Lead data science efforts for the Rentals Shopping pillar, driving strategy, modeling, experimentation, and cross-functional collaboration to improve user experience and business performance.
Top Skills: DatabricksPythonSnowflakeSQL
Reposted 15 Days AgoSaved
Remote
Chicago, IL
169K-285K Annually
Expert/Leader
169K-285K Annually
Expert/Leader
Other • Real Estate • PropTech
The Principal Data Scientist will analyze complex datasets, collaborate with teams to define metrics, mentor junior staff, and communicate insights to enhance Zillow Rentals' products and strategy.
Top Skills: DatabricksExcelPythonSQLTableau
Reposted 16 Days AgoSaved
Remote
Chicago, IL
161K-350K Annually
Senior level
161K-350K Annually
Senior level
AdTech • Digital Media • Information Technology • Other
As a Senior Principal Data Scientist, lead the application of machine learning and AI for ad measurement, optimizing advertiser outcomes through complex model and pipeline development, experimentation, and reinforcement learning systems.
Top Skills: BeamDataflowJaxPythonPyTorchSagemakerScikit-LearnSparkSQLTensorFlowVertex AiXgboost
Reposted 22 Days AgoSaved
Remote
Chicago, IL
183K-224K Annually
Senior level
183K-224K Annually
Senior level
Fintech
As a Principal Data Scientist, you'll design and deploy cutting-edge machine learning models to drive financial success for customers and guide technical teams.
Top Skills: AirflowKubernetesMachine LearningMlflowNumpyPandasScikit-LearnSpark
2 Days AgoSaved
Remote or Hybrid
Chicago, IL
138K-260K Annually
Expert/Leader
138K-260K Annually
Expert/Leader
Insurance
Lead the design and deployment of AI/ML solutions for business impact, mentor data scientists, influence analytics strategy, and establish modeling standards.
Top Skills: Azure Data FactoryAzure DatabricksAzure Machine LearningAzure Synapse AnalyticsDatabricksDelta LakeHugging FaceLangchainLlamaindexPysparkPythonSnowflakeSQLUnity Catalog
2 Days AgoSaved
Remote
Chicago, IL
142K-237K Annually
Senior level
142K-237K Annually
Senior level
Fashion
Lead the development of outfit completion models by combining client preferences and machine learning to improve personalized recommendations at Stitch Fix.
Top Skills: Deep LearningMachine LearningPythonPyTorchRecommendation SystemsSQL
Reposted 5 Hours AgoSaved
Remote
Chicago, IL
Senior level
Senior level
Fintech • Software • Financial Services
As a Senior Machine Learning Engineer, you'll build and deploy ML models for risk and fraud detection, leading technical efforts and collaborating cross-functionally.
Top Skills: Machine LearningPythonSQL
Reposted 15 Days AgoSaved
Remote
Chicago, IL
Senior level
Senior level
Biotech
The Principal Bioinformatics Data Scientist will develop advanced computational methods and ML models for genomic analysis and lead innovation in bioinformatics, driving integration of large-scale genomic data.
Top Skills: AWSAzureC/C++DatabricksGCPJavaPythonPyTorchRScikit-LearnSnowflakeSQLTensorFlowXgboost
Reposted 16 Days AgoSaved
Remote
Chicago, IL
Senior level
Senior level
Energy
The Data Scientist III/Sr/Principal role focuses on leading complex analytics initiatives, developing analytical solutions, and enforcing coding standards within the business intelligence team, utilizing SQL, Python, and R.
Top Skills: DatabricksPysparkPythonRSQL
Reposted 22 Days AgoSaved
Remote
Chicago, IL
Senior level
Senior level
Artificial Intelligence • Big Data • Internet of Things • Software
The Senior Data Scientist will lead innovative data science efforts, leveraging advanced analytics, visualization, and insights from complex datasets to boost productivity.
Top Skills: PythonRScalaSQL
Reposted 22 Days AgoSaved
Remote
Chicago, IL
Mid level
Mid level
Artificial Intelligence • Big Data • Internet of Things • Software
Entefy seeks a Senior Data Scientist with a Master's or PhD in a relevant field, and 3+ years of experience. Responsibilities include delivering advanced analytics, leading teams, and extracting insights from datasets.
Top Skills: PythonRScalaSQL
Reposted 24 Days AgoSaved
Remote
Chicago, IL
Mid level
Mid level
Agency • Machine Learning • Software • Design
Looking for a Data Scientist with experience in ML and AI alignment research to work on client projects and alignment research.
Top Skills: JavaScriptNode.jsPython
All Filters
New Jobs
Job Category
Experience
Industry
Company Name
Company Size

Sign up now Access later

Create Free Account