Top Senior Machine Learning Engineer Jobs in Chicago, IL

Reposted 17 Days AgoSaved
Hybrid
Chicago, IL
Senior level
Senior level
Software
Design, train, and implement domain-specific LLMs for automation in restoration companies. Collaborate with teams, coordinate AI engineering, and ensure model reliability.
Top Skills: Claude CodeJaxPythonPyTorch
Reposted 11 Days AgoSaved
Easy Apply
Remote or Hybrid
Chicago, IL
Easy Apply
243K-286K Annually
Senior level
243K-286K Annually
Senior level
Artificial Intelligence • Cloud • Computer Vision • Hardware • Internet of Things • Software
The Senior Machine Learning Engineer will develop ML APIs, build data pipelines, and collaborate across teams to enhance ML models and applications.
Top Skills: C++DockerGoJavaKubernetesPythonPyTorchScalaSparkTensorFlow
Reposted 13 Days AgoSaved
Remote
Chicago, IL
175K-230K Annually
Senior level
175K-230K Annually
Senior level
Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Software • Generative AI
The Sr. Machine Learning Engineer will develop and deploy ML solutions for healthcare, manage data pipelines, and work with large datasets to enhance healthcare delivery.
Top Skills: AWSC++KubernetesPythonPyTorchScikit-LearnSparkTensorFlow
Reposted 19 Days AgoSaved
Remote or Hybrid
Chicago, IL
119K-201K Annually
Senior level
119K-201K Annually
Senior level
Artificial Intelligence • Cloud • Sales • Security • Software • Cybersecurity • Data Privacy
The Senior Machine Learning Engineer will design, implement, and optimize machine learning models, drive AI initiatives, and collaborate cross-functionally to enhance SailPoint's AI capabilities.
Top Skills: AirflowAWSCloudbeesDbtFeastGoJenkinsKafkaPythonPyTorchQlikScikit-LearnShell/BashSnowflakeSQLTableauTensorFlow
Reposted 5 Days AgoSaved
In-Office
Chicago, IL
145K-237K Annually
Senior level
145K-237K Annually
Senior level
Fintech • Payments
The job involves developing and optimizing machine learning models, overseeing model risk, and collaborating with teams on AI-related projects.
Top Skills: AWSAzureGCPHadoopPythonPyTorchScikit-LearnSparkSQLTensorFlow
Reposted 2 Days AgoSaved
Remote or Hybrid
Chicago, IL
160K-195K Annually
Senior level
160K-195K Annually
Senior level
AdTech • Consumer Web • Digital Media • eCommerce • Marketing Tech
The Senior Software Engineer will design and optimize recommendation algorithms, maintain data pipelines, and improve personalized user experiences using machine learning techniques and backend engineering skills.
Top Skills: AirflowApache KafkaAws SagemakerBeamDockerElasticsearchFlinkGcp Vertex AiGrafanaJaxKibanaKubernetesNode.jsPythonPyTorchSparkTensorFlowTypescript
Reposted 2 Days AgoSaved
Easy Apply
Remote
Chicago, IL
Easy Apply
232K-310K Annually
Senior level
232K-310K Annually
Senior level
Big Data • Fintech • Mobile • Payments • Financial Services
As a Senior Staff Machine Learning Engineer at Affirm, you will lead complex ML system design and implementation, mentor engineers, and drive innovative ML strategies for financial services.
Top Skills: KubeflowMlflowPythonPyTorchRaySparkXgboost
Reposted 2 Hours AgoSaved
In-Office or Remote
Chicago, IL
190K-275K Annually
Senior level
190K-275K Annually
Senior level
Artificial Intelligence • Consumer Web • Digital Media • Machine Learning • Software
The role involves improving machine learning ranking models, implementing algorithms, and taking full ownership of machine learning systems within Quora's product.
Top Skills: C++Python
YesterdaySaved
Remote
Chicago, IL
Senior level
Senior level
Artificial Intelligence • Big Data • Machine Learning
Lead development of internal Python SDKs and agentic AI workflows, build scalable FastAPI ML services, maintain CI/CD with Jenkins/GitLab Runners, and use Galileo for model evaluation and observability to productionize autonomous systems.
Top Skills: Agentic FrameworksFastapiGalileoGitlab RunnersJenkinsMulti-Agent SystemsPythonPyvegas
Reposted YesterdaySaved
Remote
Chicago, IL
145K-250K Annually
Senior level
145K-250K Annually
Senior level
Cloud • Software
Design, optimize, and deploy deep learning models for customer behavior prediction. Perform feature engineering, implement research-informed architectures, scale training pipelines, collaborate with client teams, document findings, and uphold engineering best practices.
Top Skills: Distributed TrainingGoogle Cloud PlatformMlopsPythonPyTorchTensorFlow
Reposted 2 Days AgoSaved
Remote
Chicago, IL
165K-259K Annually
Senior level
165K-259K Annually
Senior level
Big Data • Information Technology • Machine Learning • Sales • Software • Database • Generative AI
As a Senior Machine Learning Engineer at ZoomInfo, you will enhance core datasets through ML/NLP solutions, manage entity resolution tasks, and drive cross-functional impact by mentoring teams and collaborating on ML KPIs.
Top Skills: BertGoGptGraph RagJavaPythonPyTorchRagT5TensorFlowTransformerVector Dbs
Reposted 2 Days AgoSaved
Remote
Chicago, IL
143K-197K Annually
Senior level
143K-197K Annually
Senior level
Healthtech • HR Tech
Lead design, training, fine-tuning, and deployment of ML and generative models (LLMs, diffusion). Build scalable MLOps pipelines, vectorization and data ingestion, integrate models into microservices for low-latency inference, implement evaluation/alignment/bias-mitigation, optimize models (quantization, distillation), and mentor engineers while influencing the AI product roadmap.
Top Skills: AWSCeleryDiffusion ModelsDistillationDockerJavaKotlinKubernetesLlmsLow-Latency DatabasesMicroservicesMlops FrameworksProtobufPythonQuantizationRagRelational DatabasesVector Databases
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Reposted 3 Days AgoSaved
Remote
Chicago, IL
156K-234K Annually
Senior level
156K-234K Annually
Senior level
Software
The role involves improving AI agent quality through designing experiments, maintaining evaluation infrastructure, optimizing LLM inference, and collaborating with product teams. Responsibilities include end-to-end ownership from research to deployment in a dedicated ML Engineer context.
Top Skills: DspyPythonPyTorchVllm
Reposted 3 Days AgoSaved
Remote
Chicago, IL
160K-220K Annually
Senior level
160K-220K Annually
Senior level
Big Data • Cybersecurity
Design and operate production ML systems for large-scale streaming data, ensuring reliability and performance while collaborating with researchers to integrate models into distributed systems.
Top Skills: FlinkJavaScriptKubernetesPandasPythonPyTorchScikit-LearnSparkTypescript
Reposted 18 Days AgoSaved
Hybrid
Chicago, IL
150K-190K Annually
Senior level
150K-190K Annually
Senior level
Artificial Intelligence • Computer Vision • Software • Transportation
Lead the technical direction of a computer vision platform for sidewalk inspection. Responsibilities include managing ML models, improving data pipelines, and architecting systems for terabytes of geospatial data.
Top Skills: AWSAzureCdkGCPGoJavaPythonTerraformTypescript
Reposted 4 Days AgoSaved
Remote
Chicago, IL
221K-405K Annually
Senior level
221K-405K Annually
Senior level
Social Media • Software
As a Senior Machine Learning Engineer, you will design and maintain ML systems for content recommendations, search, and spam detection, while augmenting user experience and system performance.
Top Skills: BigQueryGoPostgresPythonPyTorchRay
Reposted 4 Days AgoSaved
Remote
Chicago, IL
Senior level
Senior level
Machine Learning • Software
The Senior Machine Learning Engineer will design, prototype, build AI systems, evaluate ML models, and improve Vectara's AI Agents with a focus on reliability and performance.
Top Skills: Deep LearningMachine LearningNatural Language ProcessingPandasPythonPyTorchRetrieval-Augmented GenerationTransformers
Reposted 4 Days AgoSaved
Remote
Chicago, IL
Senior level
Senior level
Fintech • Software • Financial Services
As a Senior Machine Learning Engineer, you'll build and deploy ML models for risk and fraud detection, leading technical efforts and collaborating cross-functionally.
Top Skills: Machine LearningPythonSQL
5 Days AgoSaved
Remote
Chicago, IL
191K-225K Annually
Senior level
191K-225K Annually
Senior level
Real Estate • Travel • PropTech
Lead development and productionization of large-scale ranking and personalization ML systems. Build data pipelines, features, and models (batch and real-time), collaborate cross-functionally, run experiments, and improve infrastructure for search, recommendation, and marketplace optimization.
Top Skills: AirflowC++HiveJavaKafkaKubernetesPythonPyTorchScalaSparkTensorFlow
Reposted 5 Days AgoSaved
Remote or Hybrid
Chicago, IL
Senior level
Senior level
Artificial Intelligence • Fintech • Software • Financial Services
The Senior Machine Learning Engineer will build and own production ML systems, manage end-to-end workflow, debug issues, and mentor others.
Top Skills: JaxPythonPyTorch
Reposted 6 Days AgoSaved
Remote
Chicago, IL
Senior level
Senior level
Healthtech • Software
As a Senior Machine Learning Engineer, you'll design and develop infrastructure and models for AI-powered applications while collaborating with teams to enhance product functionality.
Top Skills: AWSDagsterDvcGCPGkeGoJavaJupyterKubeflowKubernetesLlmsMlflowPostgresPythonTriton Server
Reposted 6 Days AgoSaved
Remote
Chicago, IL
195K-251K Annually
Junior
195K-251K Annually
Junior
Information Technology • Other • Social Media
Join Nextdoor's machine learning team to build data-intensive products, develop ML models, analyze datasets, and enhance user experiences. Collaborate closely with product and data science teams.
Top Skills: Data AnalysisDeep LearningKnowledge GraphsMachine LearningNatural Language ProcessingRecommendation Systems
Reposted 6 Days AgoSaved
Remote
Chicago, IL
150K-200K Annually
Senior level
150K-200K Annually
Senior level
Healthtech • Software
As a Senior Machine Learning Engineer, you will design and implement systems for ML and NLP, optimizing models and tools for Clover's healthcare solutions.
Top Skills: LlmMachine LearningNatural Language ProcessingNumpyPandasPythonPyTorchScikit-LearnTensorFlow
Reposted 6 Days AgoSaved
Remote
Chicago, IL
120K-195K Annually
Senior level
120K-195K Annually
Senior level
Gaming
The Senior Machine Learning Engineer will develop core ML models, manage data pipelines, and collaborate with stakeholders to deliver scalable ML solutions.
Top Skills: BeamBigQueryData EngineeringGCPIcebergJavaKubernetesMachine LearningParquetPythonScalaSnowflakeSparkSQL
Reposted 6 Days AgoSaved
Remote
Chicago, IL
145K-225K Annually
Senior level
145K-225K Annually
Senior level
AdTech • Marketing Tech
Design, build, and operate production-grade ML systems for personalization, search, and recommendations. Own end-to-end pipelines from data ingestion and modeling to deployment, monitoring, and iteration, ensuring scalable, reliable, and observable services.
Top Skills: APIsAWSContainerizationEc2EmbeddingsPandasPythonRankingRecommendation SystemsRetrievalService OrchestrationSQL
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