Top Senior Machine Learning Engineer Jobs in Chicago, IL

Reposted 7 Days AgoSaved
In-Office
Chicago, IL
102K-179K Annually
Senior level
102K-179K Annually
Senior level
Analytics • Consulting
Design, build, and deploy scalable AI and machine learning solutions, leading full AI lifecycle, collaborating with teams, and ensuring systems align with client needs.
Top Skills: Agentic WorkflowsCi/CdCloud-Based DeploymentContainerizationFastapiMlflowOrchestration FrameworksPythonRag PipelinesVector Databases
Reposted 22 Days AgoSaved
Remote
Chicago, IL
165K-259K Annually
Senior level
165K-259K Annually
Senior level
Big Data • Information Technology • Machine Learning • Sales • Software • Database • Generative AI
As a Senior Machine Learning Engineer at ZoomInfo, you will enhance core datasets through ML/NLP solutions, manage entity resolution tasks, and drive cross-functional impact by mentoring teams and collaborating on ML KPIs.
Top Skills: BertGoGptGraph RagJavaPythonPyTorchRagT5TensorFlowTransformerVector Dbs
Reposted 5 Hours AgoSaved
Remote
Chicago, IL
200K-275K Annually
Senior level
200K-275K Annually
Senior level
Artificial Intelligence • Hardware • Machine Learning • Natural Language Processing • Software • Generative AI
Lead development and optimization of the compiler stack for ML systems, collaborate across teams, integrate and deploy products, map ML operations to hardware, and drive compiler infrastructure innovation and performance debugging.
Top Skills: MlirPyTorchSambanova SuiteSn40LTensorFlow
Reposted 5 Hours AgoSaved
Remote
Chicago, IL
Senior level
Senior level
Hardware • Healthtech • Machine Learning • Software
Design and implement ML infrastructure for scalable deployment, collaborate across teams, optimize ML systems, and enhance tooling.
Top Skills: AWSCloudwatchDynamoDBEcsFlinkKafkaKinesisKubeflowLambdaMlflowPythonPyTorchSagemakerTensorFlowVertex Ai
Reposted 5 Hours AgoSaved
Remote
Chicago, IL
Senior level
Senior level
Healthtech
Design, implement, and scale web and data pipeline solutions focused on generative AI and LLMs. Improve AI/ML infrastructure for model development, training, deployment, and prompt engineering. Partner with product and stakeholders to prioritize applied AI use cases, ensure PHI security and regulatory compliance, mentor junior engineers, and contribute APIs and integrations to embed generative AI into healthcare applications.
Top Skills: Ai/Ml InfrastructureAPIsGenerative AiLarge Language ModelsPrompt EngineeringSQL
Reposted 5 Hours AgoSaved
In-Office or Remote
Chicago, IL
111K-209K Annually
Senior level
111K-209K Annually
Senior level
Insurance
The Senior Databricks AI/ML Engineer will design and deploy AI/ML solutions in the insurance sector, focusing on Databricks architecture, data pipelines, and MLOps workflows, while collaborating with various teams to operationalize models and optimize processes.
Top Skills: Apache KafkaAzureAzure Cognitive ServicesAzure Event HubsAzure Ml EndpointsDatabricksMlflowPower BISnowflakeSparkSQL
Reposted 5 Hours AgoSaved
Remote
Chicago, IL
244K-305K Annually
Senior level
244K-305K Annually
Senior level
Real Estate • Travel • PropTech
Develop AI-powered solutions for personalized content and marketing. Collaborate with teams to optimize ML models and pipelines at scale, mentoring engineers and driving strategic growth initiatives.
Top Skills: AirflowC++JavaKafkaKubernetesPythonPyTorchScalaTensorFlow
Reposted 6 Hours AgoSaved
Remote
Chicago, IL
Senior level
Senior level
Software
Seeking a Senior Machine Learning Engineer to design and implement ML systems, optimize deployment, and collaborate with data teams, focusing on scalability and performance.
Top Skills: AirflowArgoAWSDatadogGCPIllamaindexKerasKubeflowKubernetesLangchainLanggraphMs AzurePythonPyTorchTensorFlow
Reposted 6 Hours AgoSaved
Remote
Chicago, IL
141K-195K Annually
Senior level
141K-195K Annually
Senior level
Database • Analytics
Responsible for designing, building, and operating AI-powered features, scalable APIs, and maintaining integrations within ClickHouse's AI/ML ecosystem.
Top Skills: Ai/MlAPIsAWSAzureGCPGoPythonTypescript
Reposted YesterdaySaved
Remote
Chicago, IL
116K-174K Annually
Senior level
116K-174K Annually
Senior level
Artificial Intelligence • Consumer Web • Information Technology • Real Estate • Software • PropTech
Build and maintain full-stack marketplace features and support ML Ops infrastructure (model deployment, feature stores, real-time pipelines, monitoring) on Chalk and Vertex AI. Collaborate with data scientists to productionize models, write well-tested code, address performance/scalability issues, and contribute to technical planning.
Top Skills: AWSAzureChalkGCPGoJavaScriptKubeflowMlflowPythonRubySQLVertex Ai
Reposted YesterdaySaved
Remote
Chicago, IL
130K-207K Annually
Senior level
130K-207K Annually
Senior level
Artificial Intelligence • Consumer Web • Information Technology • Real Estate • Software • PropTech
Build and maintain backend and full-stack marketplace features while supporting ML Ops infrastructure (model deployment, feature stores, real-time pipelines, monitoring). Collaborate with data scientists to bring models to production, write well-tested code, address performance and scalability issues, and contribute to technical planning and cross-functional communication.
Top Skills: A/B Testing FrameworksAWSAzureChalkGCPGoJavaScriptKubeflowMlflowPythonRubySQLVertex Ai
Reposted 23 Days AgoSaved
Remote
Chicago, IL
143K-197K Annually
Senior level
143K-197K Annually
Senior level
Healthtech • HR Tech
Lead design, training, fine-tuning, and deployment of ML and generative models (LLMs, diffusion). Build scalable MLOps pipelines, vectorization and data ingestion, integrate models into microservices for low-latency inference, implement evaluation/alignment/bias-mitigation, optimize models (quantization, distillation), and mentor engineers while influencing the AI product roadmap.
Top Skills: AWSCeleryDiffusion ModelsDistillationDockerJavaKotlinKubernetesLlmsLow-Latency DatabasesMicroservicesMlops FrameworksProtobufPythonQuantizationRagRelational DatabasesVector Databases
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24 Days AgoSaved
Remote
Chicago, IL
128K-267K Annually
Senior level
128K-267K Annually
Senior level
AdTech • Digital Media • Information Technology • Other
Design, build, and deploy high-throughput ML and LLM-powered personalization and agentic systems at consumer scale. Process petabyte-scale data, optimize real-time inference, implement resilient fallback paths, and balance latency, cost, and model quality while collaborating across engineering and product teams.
Top Skills: HadoopHugging FaceJavaOnnx RuntimePythonPyTorchScikit-LearnSparkTensorFlowTensorrt-LlmTritonVllm
Reposted YesterdaySaved
Remote
Chicago, IL
Senior level
Senior level
Information Technology • Software
The Senior AI/ML Engineer will develop AI systems for enterprise decision-making, focusing on LLMs and real-time data processing. Responsibilities include building detection systems, insight engines, evaluation frameworks, and collaborating with engineers to ensure robust AI product engineering.
Top Skills: AutogenAws BedrockAzure OpenaiCrewaiGcp Vertex AiKotlinLangchainLlamaindexLlmsPythonTypescript
2 Days AgoSaved
Remote
Chicago, IL
197K-307K Annually
Senior level
197K-307K Annually
Senior level
Robotics
Build and scale the ML infrastructure platform for humanoid robotics, including data processing, training, evaluation, deployment, model management, observability, and reproducible workflows. Develop cloud-native Kubernetes workflows, model registries, feature stores, experiment tracking, developer APIs, CLI tools, and ML CI/CD systems. Collaborate with AI researchers, robotics engineers, and data platform teams while mentoring junior engineers and shaping platform architecture, reliability, and scalability.
Top Skills: AirflowAWSAzureCdkCi/CdExperiment TrackingFeature StoresGCPKubeflowKubernetesMlflowMlopsModel RegistriesTerraformWeights & Biases
Reposted 24 Days AgoSaved
Remote
Chicago, IL
221K-405K Annually
Senior level
221K-405K Annually
Senior level
Social Media • Software
As a Senior Machine Learning Engineer, you will design and maintain ML systems for content recommendations, search, and spam detection, while augmenting user experience and system performance.
Top Skills: BigQueryGoPostgresPythonPyTorchRay
Reposted 24 Days AgoSaved
Remote
Chicago, IL
Senior level
Senior level
Fintech • Software • Financial Services
As a Senior Machine Learning Engineer, you'll build and deploy ML models for risk and fraud detection, leading technical efforts and collaborating cross-functionally.
Top Skills: Machine LearningPythonSQL
2 Days AgoSaved
Remote
Chicago, IL
150K-180K Annually
Senior level
150K-180K Annually
Senior level
AdTech • Marketing Tech
Designs, builds, deploys, and operates production AI/ML and LLM systems. Responsibilities include developing RAG pipelines, fine-tuning and evaluating models, managing end-to-end MLOps lifecycles, establishing monitoring and governance practices, mentoring engineers, and leading complex cross-functional client and internal initiatives.
Top Skills: Amazon BedrockAmazon SagemakerAWSAzureAzure MlCi/CdDatabricksEmbeddingsHuggingfaceLlmsMlopsPythonPyTorchRagSnowflakeSQLVector Search
Reposted 2 Days AgoSaved
Remote
Chicago, IL
140K-200K Annually
Mid level
140K-200K Annually
Mid level
Big Data • HR Tech • Mobile • Software • Database
Design and implement machine learning models to solve business problems, analyze data for insights, and optimize model performance.
Top Skills: BertConvolutional Neural NetworksGenerative Adversarial NetworksLong Short-Term MemoryMachine LearningNlpNltkPyTorchRecurrent Neural NetworksScikit-LearnSpacyTensorFlow
Reposted 2 Days AgoSaved
Remote
Chicago, IL
184K-270K Annually
Senior level
184K-270K Annually
Senior level
Financial Services
Lead and execute ML/AI strategy, design and deploy production-grade ML and GenAI solutions, mentor MLEs, collaborate with cross-functional teams, and build scalable, secure ML/LLM platforms and inference pipelines to drive business impact.
Top Skills: Apache AirflowBayesian Contextual Multi-Armed BanditsCausal Meta-LearnerDatabricksDatabricks Model ServingDeep LearningDvcFlinkGraph Neural NetworksGraphQLGrpcKafkaKinesisKubeflowLlmsMl/Llm OpsMlflowModel QuantizationModel VersioningParameter-Efficient Fine-TuningQuantization-Aware Fine-TuningRayReinforcement LearningSnowflakeSparkTransformersXgboost
Reposted 3 Days AgoSaved
Remote
Chicago, IL
128K-204K Annually
Senior level
128K-204K Annually
Senior level
Software
Design, prototype, and ship LLM- and agent-powered AI features for observability. Rapidly iterate with real users, integrate AI workflows with tooling and alerting, collaborate cross-functionally, and ensure scalable, production-ready solutions in cloud-native environments.
Top Skills: AWSAzureClaude OpusDockerGCPGemini 3 ProGenaiGpt-CodexGrafanaGrafana CloudKubernetesLlmsModel Fine-TuningPrompt EngineeringTerraform
Reposted 4 Days AgoSaved
Remote
Chicago, IL
248K-310K Annually
Senior level
248K-310K Annually
Senior level
Real Estate • Travel • PropTech
Responsible for fine-tuning state-of-the-art LLMs, optimizing models for deployment, and driving AI architectural decisions. Collaborate with cross-functional teams to develop impactful AI products.
Top Skills: PythonPyTorch
Reposted 6 Days AgoSaved
In-Office or Remote
Chicago, IL
50K-177K Annually
Senior level
50K-177K Annually
Senior level
Agency • Information Technology
Operate and monitor ML/AI models and agentic systems in production. Build AI observability, logging, tracing, and evaluation pipelines. Monitor LLM outputs, detect drift and model degradation, and maintain data/feature pipelines. Develop CI/CD, model versioning, experiment tracking, and automate alerts and incident remediation while collaborating with data scientists and platform teams.
Reposted 6 Days AgoSaved
In-Office or Remote
Chicago, IL
42K-148K Annually
Senior level
42K-148K Annually
Senior level
Agency • Information Technology
Design, develop, fine-tune, and deploy generative AI models using deep learning and transformer architectures. Collaborate cross-functionally, troubleshoot model issues, optimize performance, document work, and communicate technical concepts to non-technical stakeholders.
Top Skills: Bert)Deep LearningGansNlpPrompt EngineeringPythonPyTorchTensorFlowTransformers (GptVaes
Reposted 6 Days AgoSaved
Remote
Chicago, IL
51K-178K Annually
Senior level
51K-178K Annually
Senior level
Agency • Information Technology
Design, implement, and own end-to-end scalable ML systems and MLOps lifecycle (deployment, monitoring, metrics). Optimize models and system performance, work with Java/Python and TF/PyTorch, use CI/CD, Terraform, Docker/Kubernetes, lead inter-team communication, document work, and meet deadlines.
Top Skills: SparkCi/CdDockerGcp Ml Tech StackHadoopInfrastructure As CodeJavaKubernetesPrompt EngineeringPruningPythonPyTorchQuantizationSpeculative DecodingTensorFlowTerraform
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