Top Senior Machine Learning Engineer Jobs in Chicago, IL

Design, develop, and deploy production forecasting models and agentic AI solutions on GCP. Perform EDA, feature engineering, experiment design, and model interpretability. Build and integrate AI agents (LangChain, Vertex AI Agents) into quotation and forecasting workflows, maintain MLOps pipelines (Vertex AI Pipelines, Cloud Composer), and present results to stakeholders.

Design, build, and deploy scalable distributed deep learning pipelines and infrastructure. Optimize hardware utilization, profile and benchmark training, manage large datasets, and enable reproducible ML workflows in cloud environments. Collaborate with ML scientists and engineers to align pipelines with research goals and drive performance, reliability, and operational best practices for large-scale model development.

The Senior Machine Learning Engineer will design, train, and deploy ML models for optimizing revenue in advertising, taking ownership of product development and leading the ML discipline.

Own end-to-end ML lifecycle for pricing and underwriting: improve model accuracy and coverage, reduce infrastructure cost, deploy and monitor production models on AWS, run experiments/backtests, and collaborate with domain experts to inform model improvements and product APIs.

Build and productionize large-scale ML models and pipelines for query understanding and personalization. Work on autocomplete, query tagging/NER, query expansion, intent modeling, and LLM-powered natural-language search. Collaborate cross-functionally to design, deploy, and monitor batch and real-time systems, leveraging modern ML infrastructure and tooling to improve search relevance across Airbnb products.

Design, fine-tune, evaluate, and deploy LLM-driven, user-facing browser features using RAG, embeddings, prompt engineering, and modern ML tooling. Lead end-to-end model lifecycle, run production experiments, collaborate with product and engineering, and document and review work with an emphasis on privacy, latency, and usability.

The Senior Machine Learning Engineer will utilize deep experience and insights to enhance communication and digital interactions through advanced machine learning tools and algorithms, focusing on unstructured data.

Build and maintain ML and generative AI tooling, training and inference platform services, model evaluation and testing frameworks, and APIs to expose ML products. Deploy and manage applications across the AI/ML SDLC, mentor teammates, and write production-quality code daily.

Lead engineering execution for predictive and applied AI model portfolios across pricing, underwriting, and sales. Build, deploy, and operate ML/AI pipelines and production services in AWS/GCP, support generative and agentic AI initiatives, ensure governance, monitoring, and production readiness, and mentor junior engineers.

The Senior ML Engineer will automate component placement on PCBs, working on R&D and production using ML and optimization techniques.

The role involves owning and delivering AI-powered features for Calendly, collaborating with multiple teams, and applying machine learning solutions for product enhancement.

The role involves managing the ML lifecycle, developing scalable ML systems, and collaborating on AI-first product solutions focusing on Large Quantitative Models.

As a Senior Machine Learning Engineer, develop LLM evaluation frameworks and agentic AI workflows to extract insights from conversations and optimize customer experiences.

Design, build, and productionize ML systems focused on information extraction, retrieval, ranking, and recommendation. Own full ML lifecycle from feature engineering to deployment, observability, and evaluation. Collaborate with data, infra, and product teams to scale serving for streaming and batch inference and improve models using dataset engineering and graph/embedding techniques.

Design, build, and maintain enterprise AI-SDLC platform capabilities and LLM-powered solutions, including prompt orchestration, multi-agent frameworks, API integrations, authentication, CI/CD, automated testing, and governance. Partner with engineering teams to translate requirements, troubleshoot AI pipelines, and ensure secure, compliant, and scalable AI platform operations.

Lead design, development, and production deployment of ML models and GenAI/LLM solutions to optimize clinical trial workflows. Build scalable pipelines, monitoring, and CI/CD for robust production use. Collaborate cross-functionally, mentor junior engineers, and communicate technical results to technical and non-technical stakeholders.

Lead development and refinement of machine learning pricing models (especially reinforcement learning) for Airbnb hosts. Collaborate with data scientists, product, and engineers to design, test, integrate, and monitor models, analyze performance, and prioritize projects to improve host outcomes.

Lead development and deployment of cutting-edge ML models for pricing, design and analyze experiments, collaborate with product and engineering, present findings to stakeholders, and lead technical projects to influence team output and business metrics.

Design, implement, and scale ML-based solutions for search and advertising; define data collection, evaluation, and production serving strategies; analyze data to inform development; communicate cross-functionally; produce technical reports; and stay current with advances in LLMs, vision models, and generative AI.

The Senior AI Machine Learning Engineer will design and implement MLOps services, build AI solutions, and lead collaborations across multiple teams to enhance customer experiences.

As a Senior Machine Learning Engineer, you will enhance diffusion models, conduct research, collaborate on system implementations, and communicate findings effectively.

As a Senior Machine Learning Engineer, you will develop and deploy AI-driven products to enhance clinical trials, collaborating with teams to improve patient care through scalable machine learning solutions.

Lead development of cutting-edge LLM and Agentic AI systems for Airbnb customer support, from research and prototyping to production deployment. Collaborate with product, design, and engineering to build scalable ML infrastructure, improve model performance, and implement evaluation, fine-tuning, and guardrails for chat and voice assistants.

The Senior ML Operations Engineer is responsible for building and maintaining ML infrastructure, model deployment processes, and collaboration with data teams to optimize predictive modeling solutions.

Lead end-to-end ML system development: data exploration, model research, training, deployment, evaluation, and MLOps. Collaborate cross-functionally to prioritize claims, improve matching, measure business impact, and own a technical workstream.