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Top Chicago, IL Health Tech Companies With Best Stability & Growth (508)

ZS
Artificial Intelligence • Healthtech • Professional Services • Analytics • Consulting
Where passion changes lives

ZS is a management consulting and technology firm that partners with companies to improve life and how we live it. We transform ideas into impact by bringing together data, science, technology and human ingenuity to deliver better outcomes for all. Founded in 1983, ZS has more than 15,000+ employees in over 40 offices worldwide.

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ZS

ZS's Top Stability & Growth Strengths

Market Expansion: Headcount and footprint are described as rising to more than 15,000 employees across 40-plus offices, alongside concrete new sites in Hyderabad and a completed Chicago buildout—signals of geographic and capacity expansion. These moves indicate confidence in demand across key delivery hubs.

Innovation-Driven Growth: A dedicated Platforms & Products unit, the ZAIDYN portfolio, and AI-agent initiatives point to sustained investment in productized, AI-enabled offerings. Capability-deepening acquisitions (Digital Additive in 2024 and Torrent Consulting in 2025) further strengthen CRM and multi‑cloud life‑sciences solutions.

Strategic Partnerships: An expanded Salesforce collaboration around Agentforce and recognition as Databricks 2025 Life Sciences Partner of the Year suggest momentum in data/AI ecosystems. These alliances position the firm to capture spend where CRM, data, and AI converge in healthcare and life sciences.

Prolaio
Artificial Intelligence • Big Data • Healthtech • Mobile • Wearables • Analytics
Chicago
82 Employees
38 Benefits Hiring Now
Heart care, connected

Prolaio is a clinical intelligence company dedicated to unlocking continuous, predictive and shareable heart data to liberate patients from hospital-based reactive care and accelerate every new therapy. The company was created by cardiologists, cardiovascular practitioners, and data scientists specifically to address the world’s number one cause of death — cardiovascular disease. By combining scientific rigor with cutting‑edge technology, Prolaio aims...

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Prolaio

Prolaio's Top Stability & Growth Strengths

Innovation-Driven Growth: Regulatory momentum is evident with FDA 510(k) clearance for the eVO2peak Module and references to multiple FDA-cleared algorithms, alongside ISO 13485 and MDSAP certifications. Ongoing clinical activity and datasets (e.g., OCORO Heart Study, multi‑million hours of heart data) point to a steadily expanding product and evidence base.

Strategic Partnerships: The March 27, 2025 acquisition by Kardigan integrates Prolaio’s FDA‑cleared software, curated CV datasets, and analytics into a larger R&D platform, signaling added resources and scope. Materials indicate Prolaio continues operating independently while benefiting from Kardigan’s broader heart‑health strategy.

Strong Hiring & Retention: Hiring signals are visible through an active careers page, a stated 32 new hires in 2025, and multiple current openings across functions. Employer recognition such as “Best Places to Work 2026” and ongoing recruiting activity suggest team expansion and brand momentum.

ALIS
Healthtech • Sales • Software
Chicago
84 Employees
30 Benefits Hiring Now
ALIS is the industry leading provider of assisted living specific software.

We are a purpose driven healthcare technology company passionate about innovation and using technology to help people by solving real world problems. The ALIS team designs, builds, delivers, and supports our flagship product ALIS (pronounced “Alice” and stands for Assisted Living Integrated Solution).

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ALIS

ALIS's Top Stability & Growth Strengths

Product Line Growth: Product breadth is expanding with the launch of ALIS 500 benchmarking and the AI assistant “Ask ALIS,” alongside ongoing UX/navigation enhancements in limited release. These moves indicate continued investment in data products and core platform capabilities.

Strategic Partnerships: Partnerships are deepening through new bidirectional integrations such as Inspiren (AI fall detection), Sunbound (payments), and CCN Health (contactless vitals), signaling a growing ecosystem. These additions point to stronger enterprise pull and a more connected operating environment.

Market Expansion: Market presence is rising as the company hosts the ALIS FWD conference and maintains a dense Fall 2026 conference schedule, reflecting stepped‑up marketing and sales activity. Hiring signals and listed openings suggest capacity building to support broader go‑to‑market reach.

Tempus AI
Artificial Intelligence • Big Data • Healthtech • Machine Learning • Analytics • Biotech • Generative AI
11 Offices
3,775 Employees
72 Benefits Hiring Now
Tempus is a technology company leading the adoption of AI to advance precision medicine and patient care.

We bring together one of the world’s largest libraries of multimodal clinical and molecular data with a robust suite of AI tools to help physicians personalize care in real time, connect patients with therapies and clinical trials, and enable partners to accelerate discovery and development of new treatments. With ~8 million de-identified research records and 350+ petabytes of data, Tempus partners...

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Tempus AI

Tempus AI's Top Stability & Growth Strengths

Strong Revenue Growth: Revenue expanded rapidly, with FY2025 up 83% to about $1.27B and Q1/Q2 2026 up 36% and 22% year over year, respectively. Management also raised 2026 revenue guidance to approximately $1.595–$1.605B.

Diversified Revenue Streams: Both Diagnostics and Data & Applications are expanding, with Diagnostics up 34.7% in Q1 and 20% in Q2 2026 and Insights/data licensing up 36% in Q2 alongside about $200M in new licenses. Rising oncology test volumes (28–31% YoY) and accelerating MRD tests (~4,700 in Q4 2025 to ~9,000 in Q2 2026) reinforce multiple growth engines.

Profitability: The company achieved its first GAAP-profitable quarter in Q2 2026 (net income about $5.6M; Adjusted EBITDA ~$8.0M). Guidance points to further improvement in 2026, indicating progress toward sustained profitability.

Kalderos
Big Data • Healthtech • Software • Analytics • Pharmaceutical • Infrastructure as a Service (IaaS)
2 Offices
120 Employees
36 Benefits
Redefining how the business of healthcare performs.

Kalderos is a data infrastructure and analytics company that’s solving challenges around drug discounts in the U.S. healthcare system. Through platform technology and big data, our team is delivering smart solutions that enable healthcare stakeholders to collaborate with greater transparency and trust. We’re passionate about our mission to take on the most stubborn challenges in healthcare. We also know that...

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Kalderos

Kalderos's Top Stability & Growth Strengths

Strategic Partnerships: The acquisition by Model N positions Kalderos’s 340B and gross-to-net capabilities inside a larger life-sciences revenue platform, implying broader distribution and customer access. Integration of the Truzo claims-level visibility into Model N’s suite signals strategic value and scale-up potential.

Strong Revenue Growth: Company materials state revenue more than doubled two years in a row leading into 2023, alongside expanding customers and team. These signals point to strong pre-acquisition traction that can be leveraged under Model N.

Market Expansion: 340B drug purchases reached roughly $66.3B in 2023, indicating a large and expanding market the combined offering serves. This category tailwind supports ongoing demand for discount-management and gross-to-net solutions.

PatientPoint
AdTech • Digital Media • Healthtech • Marketing Tech • Sales • Analytics • Pharmaceutical
5 Offices
660 Employees
148 Benefits Hiring Now
Our mission is to improve health outcomes through behavior change at the point of care and beyond.

Our mission is to improve health outcomes through behavior change at the point of care and beyond. Every day, people make choices that shape their health, and at PatientPoint, we strive to support those decisions with the right information delivered at the right time. We're proud to power the largest network of digital devices in doctor's offices across the country —...

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PatientPoint

PatientPoint's Top Stability & Growth Strengths

Investor Backing & Capital Strength: Advent International agreed on August 25, 2025 to acquire PatientPoint, with reporting at more than $1.4B, providing external validation and resources to accelerate expansion. This backing is positioned to support network growth and product innovation.

Product Line Growth: In March 2026 PatientPoint launched programmatic buying (Health Audiences) and a Consumer Health Network aimed at CPG/OTC brands, expanding how advertisers can buy and who the company serves. These additions broaden monetization beyond traditional life‑sciences sponsors.

Strong Market Position & Advantage: PatientPoint reports a nationwide footprint in 30,000+ physician offices and 125,000 providers, and in April 2026 received expanded Media Rating Council accreditation across its full digital screen network. This scale and third‑party validation bolster credibility for national buys.

EliseAI
Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Real Estate
6 Offices
550 Employees
39 Benefits Hiring Now
EliseAI - an AI startup automating complex housing and healthcare systems by deeply integrating AI agents into workflows

EliseAI builds vertical AI agents for housing and healthcare — sectors that together make up nearly 40% of household spending. These agents automate high-volume workflows like leasing, maintenance, renewals, and patient intake, helping organizations cut costs, improve efficiency, and deliver better experiences. How does it work? EliseAI integrates directly into operational workflows: Housing: Manages leasing, maintenance, renewals, billing, and resident communication. Healthcare: Handles intake,...

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EliseAI

EliseAI's Top Stability & Growth Strengths

Investor Backing & Capital Strength: Large late-stage financing and valuation momentum signal strong access to capital, including a $250M Series E and corroborated unicorn-scale valuations. Capital depth is further reinforced by indications of continued fundraising interest.

Strategic Partnerships: Embedded distribution with Zillow Rentals’ AI Assist, powered by EliseAI, is reported to drive higher renter engagement and application behavior. Such channel access expands reach and evidences measurable impact in real-world funnels.

Strong Revenue Growth: Company disclosures indicate surpassing $200M in ARR with continued acceleration from earlier milestones. Adoption signals across large operators align with sustained top-line expansion.

Strata Decision Technology
Edtech • Fintech • Healthtech • Professional Services • Software • Analytics • Consulting
Chicago
800 Employees
82 Benefits Hiring Now
We empower organizations to fuel their missions.

Here at Strata, we provide financial planning software, data, and insights to drive decisions and performance for organizations spanning the healthcare, higher education, and financial services industries.

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Strata Decision Technology

Strata Decision Technology's Top Stability & Growth Strengths

Diversified Customer Base: Company materials indicate Strata now serves more than 2,300 organizations across healthcare, higher education, and financial services, with recent moves extending further into financial institutions. The Syntellis combination and the 2026 c. myers acquisition broaden exposure beyond hospitals, diversifying growth drivers.

Product Line Growth: New offerings such as StrataJazz Position Control (June 2025) and AI-driven Predictive Analytics (March 2026) expand the platform’s capabilities. These launches address labor optimization and earlier financial risk detection, signaling continued investment in the product suite.

Strategic Partnerships: A March 2025 collaboration with Snowflake is aimed at handling explosive growth in customer data needs and scaling a large comparable healthcare financial dataset. This alignment supports platform performance and data accessibility as the customer base grows.

Clinify Health
Healthtech
Chicago
13 Employees

Clinify Health is a digital health company that works with healthcare organizations caring for populations in underserved communities to achieve financial stability through value-based decision-optimization that enables providers to succeed in alternative payment arrangements.

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Clinify Health
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Player's Health
Healthtech • Kids + Family
Chicago
8 Employees

Player’s Health is the first universal health management and compliance application for youth athletes.  Our HIPAA compliant mobile application provides athletic programs with players' essential medical information and streamlines the injury reporting process in an easy to use digital platform. Coaches, trainers, parents and athletic directors can monitor the health and progression of an injured player.  Parents are instantly notified...

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Player's Health
Acceleron Corp
Cloud • Healthtech • Mobile • Software • Consulting
Chicago
8 Employees
14 Benefits

At Acceleron, we create well-engineered software with a team of technology craftsmen who love to code and take pride in their work. Our core competencies are the construction of: Beautifully designed, well-architected and performant iOS, Android and web apps Thoughtfully engineered, extensible and efficient APIs and backend services Secure, scalable servers and related infrastructure on AWS and Google Cloud Technology audits for GDPR and CCPA...

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Acceleron Corp
United Natural Foods
Food • Healthtech
49 Offices
15,777 Employees
20 Benefits

UNFI is North America’s Premier Food Wholesaler. We transform the world of food for our associates, customers, suppliers and the families we serve every day. With deeper full store selection and compelling brands for every aisle, built on an unmatched heritage in great food and fresh thinking. And smarter food solutions, from fulfillment to insights and beyond, that help entrepreneurs...

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United Natural Foods
SonarMD
Artificial Intelligence • Healthtech • App development
Chicago
20 Employees
2 Benefits
SonarMD is the leading value-based care company for gut health.

SonarMD was founded on the belief that there had to be a better way to gain control and get ahead of both the debilitating disease and skyrocketing costs. Enabling early intervention and management by enhancing the level of care offered through providers. SonarMD is the leading, value-based care coordination solution for complex chronic GI diseases. Our longitudinal, high-engagement platform makes it...

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SonarMD
KeyCare
Healthtech
Fully Remote
25 Employees
Providing health systems with access to a virtual care workforce on Epic.

KeyCare provides health systems access to a nationwide network of Virtualists that are working on our instance of Epic. This allows the Virtualists working on KeyCare to more easily connect into health systems using Epic or other meaningful use certified EMRs, with a goal to help them improve access and quality for their patient population, while decreasing physician burnout and...

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KeyCare
1776 Senior Care
Healthtech
Glen Ellyn
51 Employees

On-Demand Senior Care, In-Home Health Care, Senior Care Staffing

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1776 Senior Care
CareTree
Enterprise Web • Healthtech
Chicago

CareTree is an online platform that improves caregiver operations and facilitates timely communication with families.  CareTree does this by replacing paper records in the home health and senior care industries with an online portal that centralizes information and automates communication with care stakeholders (be it the individual, caregivers, family, or doctors).Finalist - Chicago Lean Startup ChallengeFinalist - AARP Innovate@50+, 1...

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CareTree
Quantum Institute
Vernon Hills

Quantum Institute has dedicated itself to leading a worldwide revolution in concussion management and athletic development by optimizing medically cleared technology with proven neurodiagnostics. The patent-pending Quantum process  provides athletes of all ages with unique tools, technologies, and training programs to maximize mind and body strengthening and achieve performance excellence both on and off the field of play.The Quantum Q-MAP®...

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Quantum Institute
Rally Health
Healthtech
6 Offices
1,530 Employees
40 Benefits
Rally Health is an intuitive end-to-end experience, putting health in the hands of the individual.

Rally Health, Inc. is a consumer-centric health experience company that makes it easy for individuals to take charge of their health and collaborates with health plans, care providers, and employers to engage consumers. The team behind Rally Health has been working together since 2010 to transform the consumer health industry.

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Rally Health
Takeda
Healthtech • Software • Analytics • Biotech • Pharmaceutical • Manufacturing
29 Offices
50,000 Employees
42 Benefits
Takeda exists to create better health for people, brighter future for the world.

For over 240 years, Takeda’s propensity to evolve has driven the next generation of innovation, and as a future-focused organization, we’re continuing to drive forward with endurance in our steadfast pursuit to achieve the best outcomes for our patients in a rapidly changing world.  We have been preparing for this period of value creation by investing in data, digital and...

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Takeda

Takeda's Top Stability & Growth Strengths

Strong Market Position & Advantage: Takeda is consistently placed among the global top 15–20 by revenue and is a clear category leader in GI/IBD, plasma-derived therapies, and dengue vaccines with broad international authorizations and WHO support. Subcutaneous ENTYVIO and new oncology approvals like FRUZAQLA broaden real‑world use and extend reach.

Profitability: Reported FY2025 operating profit rose 19.3% year over year and EPS nearly doubled despite a slight revenue decline, supported by lower amortization and restructuring expense. Core profitability remained broadly stable as Growth & Launch Products expanded their share.

Future-Ready Strategy: Management is investing through FY2026 to convert a late‑stage pipeline (e.g., oveporexton, rusfertide, zasocitinib) into multiple launches, with Growth & Launch Products prioritized as near‑term engines. A multi‑year transformation and efficiency program targeting significant savings by FY2028 is intended to fund launches and strengthen competitiveness.

Sonder (sonder.io)
Healthtech • Software
36 Offices
247 Employees
34 Benefits

At Sonder, we help organisations improve the wellbeing of their people and empower them to be at their best. We do this by providing leaders with a comprehensive care platform that delivers support through the right care, at the right time. Allowing people take control of their wellbeing in a way that suits them - on their terms, on their...

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Sonder (sonder.io)

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