Top Senior Engineer Jobs in Chicago, IL

Provides technical leadership for designing, developing, implementing, and supporting Microsoft Dataverse, Dynamics 365, and Power Platform solutions. Translates architecture and business requirements into technical approaches, leads proofs of concept and troubleshooting, guides engineers, and develops complex components using C#, .NET, JavaScript, Azure services, APIs, plug-ins, and PCF controls. Partners with architecture, delivery, quality, and DevOps teams on integrations, CI/CD, application lifecycle management, releases, and production support.

Leads verification, validation, risk assessments, and computer system validation for AI, SaaS, host systems, and medical device software. Develops validation documentation, policies, procedures, and testing strategies aligned with FDA, ISO 13485, GAMP5, and software lifecycle standards. Supports change management, incident processes, audits, inspections, and regulatory compliance while mentoring test engineers and collaborating cross-functionally.

Architect and own marketing data infrastructure, including Databricks pipelines, Gold Layer tables, semantic models, and ETL/ELT workflows. Build trusted data products for analytics, automation, and AI agents; translate ambiguous business needs into scalable solutions; lead cross-team initiatives; ensure reliability and data quality; mentor engineers and analysts; and develop, evaluate, and monitor production LLM and agent systems using Python and SQL.

Lead QA efforts by designing and executing test strategies, creating automated and manual tests, tracking defects, maintaining traceability matrices, reporting findings, and collaborating with cross-functional teams to ensure product reliability and continuous improvement.

Develop machine learning models, predictive solutions, data pipelines, data models, and feature engineering workflows. Analyze large datasets, validate model outputs, document assumptions, and translate business needs into technical requirements and recommendations. Collaborate with stakeholders, refine analytical use cases, support solution prototyping, and guide junior team members through coaching and technical feedback.

Design and build web and mobile trading applications using React/React Native and .NET; extend WebSocket/REST APIs; process streaming market data; collaborate with product and vendors; troubleshoot urgent issues; apply AI coding assistants responsibly.

Lead cross-functional teams to design, build, and deliver high-quality web, mobile, and embedded software. Provide technical direction, mentor developers, promote best practices (TDD, Agile), communicate with clients, and contribute to company technical outreach. Balance hands-on coding with architecture, team coaching, and client-facing responsibilities.

The Senior Software Engineer will design and build cloud-native applications, lead technical initiatives, and mentor junior developers while collaborating with the product team.

Leads technical strategy, architecture, operational excellence, mentorship, and multi-team software delivery. Designs maintainable distributed systems using microservices, improves monitoring and operational maturity, drives innovation, and collaborates with stakeholders across departments. Requires 9+ years of enterprise software development experience, public-cloud expertise, strong leadership, communication, analytical, documentation, and problem-solving skills.

Leads the design and development of full-stack systems supporting diagnostics and genomic data processing. Responsibilities include architecting microservices, scaling bioinformatics workflows, developing AI-assisted applications, optimizing PostgreSQL and Redis, managing GCP infrastructure and CI/CD, and integrating APIs and agentic workflows. The role also involves technical leadership, mentoring, cross-team collaboration, architectural decision-making, and bridging software engineering with computational biology teams.

Lead the design, development, and operation of Expedia’s shared GenAI platform, including scalable backend services, multi-agent infrastructure, APIs, guardrails, intelligent LLM routing, model deployments, fine-tuning pipelines, evaluation standards, and observability. Partner with product and engineering teams to deliver secure, reliable, reusable AI capabilities at global scale.

Leads global teams developing production AI, GenAI, RAG, agentic workflow, and MLOps solutions for health systems and health plans. Translates clinical, financial, and operational challenges into HIPAA-compliant use cases involving clinical decision support, population health, revenue cycle, research, and optimization. Oversees healthcare data science engagements, model governance, executive stakeholder communications, client delivery, and team development.

Develops and maintains Python data pipelines and business data objects. Designs software solutions, implements source-to-target mappings, builds CI/CD pipelines, and performs unit and integration testing. Resolves complex technical problems, interprets design requirements, and promotes software quality and team improvement. The role requires onsite work five days per week in Chicago, Peoria, or Dallas.

Leads security engineering implementations for identity management, authorization, observability, and microservice security. The role improves security services, frameworks, tooling, and standards; configures Auth0, Okta, Auth0-FGA, Chronicle, Terraform, and GCP; partners with product and engineering teams; and drives reliable, scalable security solutions across the organization.

Design, build, and maintain blockchain and payments infrastructure; develop scalable microservices and secure RESTful APIs to transfer value across blockchain and banking protocols; integrate with banks and fintech; own system design, testing, deployment, and troubleshooting; ensure reliability, code quality, and strong test coverage while collaborating with product and engineering teams.

Lead SRE practices for highly available cloud-native platforms across AWS, Azure, and Kubernetes. Build observability, dashboards, alerting, infrastructure automation, CI/CD, GitOps, and self-healing capabilities. Lead incident response, root cause analysis, and remediation while improving reliability, scalability, and operational excellence. Partner with engineering, architecture, security, and platform teams, drive AI-enabled operations, and mentor engineers on SRE and cloud-native best practices.

Conduct on-site and desktop risk assessments for conventional and renewable power facilities and construction projects. Evaluate hazards, loss drivers, mitigation strategies, plant protection, and management systems to support underwriting decisions. Provide technical input to underwriters, claims teams, clients, and insureds; maintain account files; follow up on risk improvements; support claims analysis and business development. Regular travel is required.

Provides technical leadership for pre-sales activities, designing integrated technology solutions and advising customers on Rubrik’s cyber resilience, observability, and remediation products. Leads technical sales calls, presentations, demonstrations, opportunity qualification, and solution architecture while partnering with account teams, customers, and internal resources. Requires expertise in cloud data management, backup, disaster recovery, analytics, distributed architectures, file systems, and SAN storage.

Design, develop, deploy, and maintain high-volume backend systems supporting customer funding, trading, and back-office operations. Lead development practices through code reviews, mentoring, architecture guidance, and quality ownership. Build reliable, observable software using Python and TypeScript, collaborate with finance and trading teams, improve operational efficiency, document workflows, and oversee projects from design through iteration.

Leads cloud asset intelligence and inventory initiatives, defining technical vision, architecture standards, and platform strategy. Designs scalable, secure, multi-tenant cloud platforms; modernizes monoliths into microservices and event-driven systems; and applies AI and automation to improve cloud operations. The role drives cross-divisional architecture, engineering standards, operational excellence, and executive influence while mentoring senior engineers and strengthening organizational capabilities.

Designs, engineers, and automates highly available cloud infrastructure and platforms for a global IoT service. Responsibilities include evolving PaaS implementations, managing Kubernetes and infrastructure-as-code solutions, monitoring and troubleshooting security and infrastructure events, conducting root-cause analysis, collaborating on architecture and security, and mentoring junior engineers. The role also supports technology roadmaps, cloud cost optimization, and infrastructure initiatives across distributed teams.

Lead mobile architecture and develop scalable Flutter applications for iOS and Android. Own features through testing, release, monitoring, and debugging; guide technical roadmaps; optimize performance and reliability; improve observability and crash analytics; collaborate with Product and Design; mentor engineers; and promote engineering excellence.

Maintains and repairs material handling equipment, building systems, grounds, and facility infrastructure at a distribution center. The role requires anhydrous ammonia experience, troubleshooting mechanical, hydraulic, electrical, pneumatic, and electronic systems, operating powered equipment, supporting fire protection systems, handling hazardous materials, and following safety and operational procedures.

Architects, deploys, and operates scalable data platform infrastructure supporting analytics. Responsibilities include administering Airflow and Superset, managing Terraform infrastructure, building CI/CD pipelines, enforcing security and compliance, developing DBT data models, cataloging assets in OpenMetadata, writing Python automation, and mentoring engineers. The role requires extensive infrastructure and data engineering experience across cloud platforms, containers, data security, and workflow orchestration.

Leads quality engineering activities for medical device and regulated products, including process validation, testing, SPC, supplier qualification, CAPA, SCARs, design controls, risk management, DMRs, CE technical files, and 510(k) documentation. Investigates nonconformances, ensures regulatory compliance, conducts quality reviews, coordinates laboratory testing, and trains team members. Requires cross-functional leadership, advanced Excel skills, and up to 15% travel.