Top Director of Operations Jobs in Chicago, IL

The Director of Operations oversees 6 to 9 restaurant locations, focusing on operational excellence, team development, and financial performance.

Lead vision, strategy, and operations for live events, promotions, and player engagement to drive retention and monetization. Build and grow the live ops team, set KPIs, ensure flawless event execution, resolve operational issues, and partner cross-functionally with Product, Engineering, Marketing, and Commercial Insights to optimize promotion economics and long-term player experience.

No specific responsibilities were listed. Likely to lead and scale operations for digital assets, manage brokerage/clearing operational processes, ensure compliance, and coordinate cross-functional teams.

Lead national multi‑state operations for GT Independence, driving operational excellence, compliance, growth, and quality. Oversee regional Directors, standardize scalable processes, monitor KPIs, support strategic expansion, and represent the organization with stakeholders and state agencies.

Lead regional program and operations for multiple Ronald McDonald House and Family Room sites: manage staff and volunteers, oversee 24/7 facility operations and facilities management, implement program strategy and continuous improvement, build hospital partnerships, manage budgets and reporting, and ensure family-centered care and compliance with organizational policies.

Lead global launch operations for Microsoft Advertising, governing end-to-end GTM processes, cross-functional alignment, product and seller readiness, risk mitigation, and program execution. Manage teams, stakeholders, and launch governance to ensure compliant, scalable launches that support order-to-cash accuracy, revenue recognition, and operational readiness at scale.

Leads Microsoft Advertising’s Sales Compensation Solutions team and owns compensation plan design, segmentation, sales planning, quota and payout execution, governance, and role excellence. Advises senior leaders on sales investments and strategy, builds high-performing teams, aligns cross-functional partners, and advances AI-enabled sales planning operations, automation, and process simplification.

The Director of Operations partners with local leaders to enhance brokerage operations, oversee teams, manage budgets, and improve organizational efficiency. This role involves strategic planning, people management, and collaborating across corporate functions to drive business goals effectively.

Leads organization-wide progress monitoring and reporting, including board updates, data analysis, and data-driven narratives. Coordinates cross-functional partnerships among Product, Systems, and External Affairs, supports internal and external councils, and owns the Insights & Strategy team’s planning, meeting cadence, knowledge management, and process improvement. Requires strong writing, strategic thinking, quantitative analysis, collaboration, discretion, and operational execution.

Senior RevOps leader partnering with the CRO to own GTM operations: manage revenue tech stack, ensure data integrity and forecasting accuracy, optimize lead-to-renewal lifecycle, build revenue analytics and dashboards, and lead cross-functional initiatives to drive ARR growth and operational scale.

Provide strategic and operational support for alumni relations and development, coordinating donor stewardship, alumni engagement, volunteer activities, and fundraising. Manage communications, donor acknowledgments, stewardship reports, and presentations. Maintain and analyze constituent and fundraising data in Salesforce and PowerSchool, prepare reports and dashboards, support gift administration and prospect research, plan events, improve workflows, and assist with office and scheduling tasks to advance fundraising goals.

Leads healthcare interoperability strategy and data operations across payer and provider ecosystems. Oversees clinical and administrative data exchange, operational and analytic data platforms, integration processes, APIs, data feeds, quality control, change management, production support, governance partnerships, and continuous improvement. Manages teams, staffing, performance, budgets, stakeholder support, and reliable delivery of healthcare data assets supporting claims, utilization management, risk, case management, and quality programs.

The Director of Strategy & Operations at The Hackett Group leads business transformations for clients, overseeing projects and managing client relationships, while also focusing on business development and ensuring project success.

Lead and grow a defined contribution retirement plan practice by overseeing plan administration, compliance, partner support, onboarding/book conversions, client and advisor relationships, team development, and P&L management. Act as technical escalation, support M&A integrations, implement scalable processes, and drive operational excellence and profitability.

Lead client experience and agency operations for paid media accounts, overseeing media buying team performance, client retention, reporting, and process development. Own client leadership meetings, track KPIs (cost per appointment, show and close rates), and build scalable operational systems to improve efficiency and margin.

Leads enterprise revenue operations analytics and performance management. Owns KPI monitoring, forecasting, recurring analytical models, dashboards, root-cause analysis, intervention workflows, and executive reporting. Partners across Growth, Marketing, Operations, Clinical, HR, Finance, and Contact Center teams to improve data integrity, accountability, performance visibility, forecasting accuracy, patient visits, revenue, and operational consistency.

Leads research commercialization, industry-sponsored clinical trials, strategic partnerships, technology licensing, and collaborative research programs. Develops portfolio strategy, budgets, forecasts, pricing, and negotiation frameworks; oversees contracts, regulatory requirements, staffing, risk management, performance metrics, and cross-functional execution. Serves as a senior advisor to scientific and executive leadership while cultivating relationships with pharmaceutical, biotechnology, medical device, digital health, and academic partners.

Senior operations leader overseeing inbound/outbound warehouse, transportation, fleet, facilities, and safety. Manages budgets, compliance, continuous improvement, staffing, vendor relations, and emergency response to meet performance metrics and prepare for VP role.

Directs strategic planning and operational support for aviation maintenance, focusing on cost savings, vendor agreements, procurement optimization, rental asset scheduling, forecasting, dashboards, and workforce growth planning. Partners with finance, technical, regional, and parts-and-engines teams to improve maintenance event decisions, control costs, strengthen vendor performance, and provide executive leadership with actionable operational and financial insights.

Leads operational performance, service delivery, financial management, facilities, vendor relationships, compliance, and administrative functions for Cushman & Wakefield’s Chicago market and headquarters. Manages operations and facilities leaders and support staff, oversees budgeting and forecasting, drives process improvements, supports hiring and performance management, ensures CRM and Workday adoption, coordinates office moves and business continuity, and partners with market, regional, HR, finance, legal, marketing, IT, and brokerage leadership.

Leads Ingredion’s global Operations digital strategy across manufacturing, supply chain, procurement, quality, and EH&SS. Owns technology roadmaps, enterprise portfolio governance, investment prioritization, vendor relationships, and large-scale transformation initiatives. Advises executives, drives adoption of AI, analytics, automation, and RPA, establishes value-based KPIs, and leads a global team of digital partners, analysts, and architects. The role requires extensive global leadership, enterprise technology expertise, financial acumen, and experience managing complex transformation programs.

Provides strategic financial leadership for the Data Science Institute, overseeing budgeting, forecasting, financial modeling, reporting, accounting, procurement, grants, contracts, revenue analysis, and expense optimization. Manages operations staff and facilities planning, maintenance, renovations, and space operations. Advises institute leadership and university financial stakeholders, ensures compliance with financial policies and systems, and develops processes, metrics, and reports to improve decision-making and operational efficiency.

Manage day-to-day operations and project delivery for systems, network, storage, and HPC infrastructure. Lead system administrators and research support staff, plan budgets, ensure disaster recovery and high availability, collaborate with faculty on research computing solutions, enforce security policies, and coordinate external HPC partnerships.

Partners with the CTO and CPO to translate product and technology strategy into predictable execution. Owns portfolio governance, executive cadences, planning, resource allocation, investment trade-offs, strategic initiatives, decision framing, accountability, and cross-functional alignment. Provides executive visibility into outcomes, risks, milestones, ROI, and budgets across Product and Technology. Also operationalizes AI tooling and evolves AI-first operating models to improve developer productivity and delivery velocity.

Provides enterprise leadership for pharmacy operations across START’s U.S. clinical research sites. Responsibilities include standardizing investigational drug services, sterile compounding, clinical documentation, procurement, compliance, quality systems, KPIs, technology strategy, audits, and site launches. The role develops pharmacy leaders, manages budgets and change initiatives, ensures regulatory and GCP readiness, and serves as a subject-matter expert in investigational drug management for early-phase oncology trials.