Top Senior Data Science Jobs in Chicago, IL

Develop and deploy machine learning algorithms that improve real-time device identification and fraud detection. Own data science projects from experimentation through production, including supervised, semi-supervised, and unsupervised learning, real-time inference, training automation, exploratory analysis, and model-to-service integration. Contribute to engineering best practices, collaborate within a global remote team, and participate in a shared on-call rotation.

Lead data science projects from ideation through enterprise impact, building scalable and well-tested solutions that improve healthcare outcomes. Apply probability, statistics, machine learning, SQL, and Python to develop data-driven products and insights. Partner with stakeholders, assess product performance, identify strategic improvements, mitigate risks, and mentor teammates while aligning initiatives with business objectives.

Build and productionize traditional machine learning models, owning feature engineering, validation, deployment, monitoring, drift detection, and retraining. Develop LLM-powered agentic tools, dashboards, self-serve analytics products, and automated insight pipelines. Partner with engineering and business stakeholders, write production-grade Python and SQL, drive adoption, improve data quality, and establish responsible AI workflows for a regulated industry.

Leads analytical and scientific strategy for Fetch’s Play and Rewarded Apps businesses. Develops predictive and machine learning models, experimentation frameworks, causal analyses, feature pipelines, and measurement systems using Python and SQL. Partners with Product, Marketing, Engineering, and business leaders to improve monetization, engagement, retention, personalization, and marketplace outcomes. Translates complex findings into strategic recommendations, mentors data scientists and analysts, and establishes analytical best practices.

Lead ecosystem-level data science and econometric analyses across Xbox, Game Pass, Console, PC, and Store experiences. Evaluate growth, engagement, monetization, experiments, incrementality, and investment ROI using statistical and causal inference methods. Build reusable analytical products and self-service capabilities, influence executive decisions, and mentor team members.

The Lead Data Scientist will enhance analytics through predictive modeling and data engineering, focusing on quality, feature generation, and continuous learning.

Lead Data Scientist partners with business leaders to identify opportunities, design, develop, and deploy advanced analytics and ML solutions. Responsibilities include data preparation, modeling, feature engineering, delivering insights and visualizations, establishing standards, and directing associate data scientists, contractors, and consultants to produce measurable business value.

Lead product and program analytics for Microsoft skilling experiences: design learner journey/funnel analyses, define success metrics, run experiments and causal analyses, build proficiency/competency models, shape telemetry and scalable reporting, recommend content and curriculum improvements, and mentor other data scientists to drive product decisions and learning outcomes.

Lead development and productionization of telematics pricing and underwriting models. Responsibilities span statistical modeling, feature engineering, dataset and pipeline development, model deployment, monitoring, data quality validation, troubleshooting, regulatory support, and collaboration with pricing, actuarial, product, engineering, and compliance teams.

Own the analytical function for a core business area such as growth, product, AI and automation, or strategic partnerships. Define business problems, metrics, reports, analyses, and experiments; generate actionable insights; and influence leadership decisions. The role requires independently structuring data, solving ambiguous problems, communicating findings clearly, and driving recommendations through execution.

Leads product analytics and experimentation for Yahoo’s homepage. Defines product metrics, designs and interprets complex A/B tests, applies advanced statistical methods, and delivers insights influencing product strategy. Builds dashboards, scalable data assets, datasets, and instrumentation with Data Engineering. Uses AI-assisted tools to automate analytics workflows while validating generated code and queries. Partners cross-functionally with Product, Engineering, and Design, and mentors junior analysts while promoting rigorous experimentation and data quality practices.

Own end-to-end data science for a business unit across growth, product, AI and automation, or strategic partnerships. Define metrics, build reports, analyze data, design experiments, identify insights, and influence leadership decisions. The role requires independently structuring ambiguous problems, communicating recommendations clearly, and driving measurable outcomes through execution.

Design, deploy, and manage machine learning models supporting client acquisition, retention, and reactivation. Develop Next Best Action, CRM, paid media, and personalization solutions using LLMs and traditional ML. Design and interpret experiments, analyze large-scale datasets, communicate recommendations to stakeholders, and collaborate with product, design, and engineering teams on product and infrastructure roadmaps.

Lead data science engagements with customers to acquire, clean, analyze, and model data; develop scalable operational models and evaluation methods; coach engineers on best practices; drive solution strategy, ethics, and industry thought leadership; write extensible code and collaborate across teams to deliver cloud-based AI solutions.

Develop and optimize machine learning and statistical models for fraud detection and anti-money laundering. Analyze large datasets to identify fraudulent patterns, build scalable data pipelines and features, evaluate model performance, and collaborate with engineering, product, and operations teams. Communicate insights to technical and non-technical stakeholders while maintaining data privacy and security compliance. The role offers significant ownership in building Oscilar’s early machine learning stack within a remote-first startup.

Tune AML and fraud detection models using customers’ live transaction data. Investigate missed cases, alert quality, pattern drift, and false positives; validate changes through backtesting and sample review; document regulatory rationale; and present model performance and business value to compliance, risk, and data science stakeholders. Partner with customer teams on account strategy and relay customer-specific or systemic findings to product and model functions.

Own mobile marketing analytics frameworks, dashboards, cohort and campaign analysis, profitability modeling, audience strategy, and incrementality experiments. Analyze attribution, retention, LTV, CAC, ROAS, payback, creative performance, and marketplace dynamics. Partner with marketing, finance, and leadership to guide spend allocation and growth decisions while navigating mobile privacy and attribution challenges.

Own sales forecasting and revenue analytics by developing statistical and machine learning models across products, regions, and time horizons. Lead the full machine learning lifecycle from feature engineering through deployment, monitoring, and explainability. Translate forecasts into business recommendations, deliver production data products, mentor junior data scientists, and provide technical leadership across analytics and sales teams.

As a Staff Data Scientist, you will analyze large-scale broadband data, develop and validate ML models, and integrate solutions into Calix Cloud, collaborating with teams for enhanced network intelligence and subscriber experience.

Leads end-to-end applied data science and AI workstreams for predictive underwriting and pricing, including problem framing, feature engineering, model development, validation, deployment, monitoring, and business-impact measurement. Builds explainable, governed, and reusable production models using healthcare and insurance data. Partners with underwriting, business, product, engineering, and legal teams; mentors others; and advances responsible AI, MLOps, model governance, and shared data science practices.

The Senior Data Scientist will analyze data to drive product strategy, optimize performance, and support product launches, collaborating with cross-functional teams.

As a Senior Data Scientist, you'll develop fraud detection models, perform detailed analyses, and work closely with teams to drive product innovation and business outcomes.

As a Senior Staff Data Scientist, you will lead data science initiatives, mentor teams, develop frameworks for experimentation, and collaborate across departments to drive decision-making through data insights.

Lead the strategic direction and evolution of Netflix’s company-wide Experimentation Platform. Establish rigorous causal inference and experimentation standards, automate trust and validation practices, consolidate fragmented systems, shape platform product roadmaps, and collaborate with data science and engineering leaders. Translate experimentation needs into scalable tools, influence adoption across teams, mentor colleagues, and ensure reliable experiment allocation, measurement, analysis, and reporting.

Develop advanced data science and AI/ML solutions using complex healthcare data. Apply statistical modeling, machine learning, NLP, and LLM techniques, including RAG and prompt optimization. Build production-ready workflows integrating models with APIs, data pipelines, enterprise applications, and cloud platforms. Analyze data quality and model performance, communicate findings to technical and executive audiences, and collaborate across product, engineering, clinical, technology, and business teams.