Top Senior Machine Learning Jobs in Chicago, IL

Reposted 8 Days AgoSaved
Hybrid
Chicago, IL
179K-225K Annually
Senior level
179K-225K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
Responsible for validating payment network models, including fraud and AML. Engage with stakeholders, improve model accuracy, and leverage innovative technology for data analysis.
Top Skills: AWSMachine LearningPythonRRelational DatabasesScalaStatistical Modeling
Reposted 2 Days AgoSaved
Easy Apply
Remote
Chicago, IL
Easy Apply
196K-247K Annually
Senior level
196K-247K Annually
Senior level
Artificial Intelligence • Fintech • Healthtech • Software
Lead the development of machine learning systems for Cedar Pay's Personalization Engine, manage ML engineers, and ensure ML model effectiveness.
Top Skills: Machine LearningPythonSQL
Reposted 6 Days AgoSaved
Easy Apply
Remote
Chicago, IL
Easy Apply
225K-245K Annually
Senior level
225K-245K Annually
Senior level
Healthtech • Software
The Staff Machine Learning Engineer will lead ML initiatives, develop ML systems, collaborate with cross-functional teams, and mentor junior engineers to optimize healthcare intake workflows using advanced machine learning techniques.
Top Skills: AWSCloud PlatformsDeep LearningMachine LearningPythonPyTorch
7 Days AgoSaved
Easy Apply
Remote or Hybrid
Chicago, IL
Easy Apply
128K-240K Annually
Senior level
128K-240K Annually
Senior level
Fintech • Mobile • Software • Financial Services
Lead AML model development, optimization, validation, and governance for transaction and customer screening across banking, brokerage, and lending. Build ML/statistical models, maintain vendor solutions, ensure regulatory compliance, document methodologies, produce AML dashboards, and support audits, risk assessments, and stakeholder communications.
Top Skills: DatadogDockerKubernetesLexisnexisMachine LearningMonte CarloPythonSnowflakeSQLTableauTerraformVerafin
Reposted 12 Days AgoSaved
Easy Apply
Remote
Chicago, IL
Easy Apply
232K-310K Annually
Senior level
232K-310K Annually
Senior level
Big Data • Fintech • Mobile • Payments • Financial Services
Lead the development of fraud prediction models using machine learning, collaborating across teams to build, scale, and monitor models in production.
Top Skills: AirflowCatboostKubeflowLightgbmMachine LearningMlflowPythonPyTorchSparkXgboost
Reposted 12 Days AgoSaved
Easy Apply
Remote
Chicago, IL
Easy Apply
200K-275K Annually
Senior level
200K-275K Annually
Senior level
Big Data • Fintech • Mobile • Payments • Financial Services
Lead a team of ML engineers to develop fraud detection models, defining strategies, driving model evolution, and ensuring effective integration with cross-functional teams.
Top Skills: Data PipelinesDeep LearningGradient-Boosted TreesMachine LearningRepresentation LearningScalable SystemsTransformer-Based Models
52 Minutes AgoSaved
Hybrid
Chicago, IL
101K-205K Annually
Senior level
101K-205K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
Lead product efforts for machine learning-driven marketing and acquisition products. Collaborate with data scientists, engineers, and designers to define acceptance criteria, break down epics into MVP features and user stories, prioritize roadmaps, manage agile delivery, and drive stakeholder alignment to build scalable ML product platforms.
Reposted 18 Hours AgoSaved
In-Office or Remote
Chicago, IL
113K-193K Annually
Senior level
113K-193K Annually
Senior level
Artificial Intelligence • Big Data • Healthtech • Information Technology • Machine Learning • Software • Analytics
Lead design and delivery of scalable Amazon Connect voice and chat solutions. Build Lambda-based integrations, integrate Lex bots and external systems, optimize routing/queues, ensure high availability and monitoring, lead production support, RCA, and continuous improvement for contact center platforms.
Top Skills: Amazon Api GatewayAmazon ConnectAmazon LexAPIsAws LambdaIvrNode.jsTypescript
2 Hours AgoSaved
In-Office
Chicago, IL
116K-193K Annually
Senior level
116K-193K Annually
Senior level
Automotive • Insurance
Lead a small team to design, build, deploy, and monitor ML/AI solutions for Claims (fraud, triage, severity, litigation, subrogation). Manage projects, collaborate with engineering and IT, follow model governance, and mentor staff.
Top Skills: Agentic AiAIGitMachine LearningModel Lifecycle ManagementPythonSQL
YesterdaySaved
Hybrid
Chicago, IL
120K-140K Annually
Senior level
120K-140K Annually
Senior level
Hardware • Security • Software • Cybersecurity
Lead the AI & Analytics stream to design, build, and deploy predictive and prescriptive ML models, integrate analytics into enterprise platforms (Salesforce, ServiceNow), automate root-cause and log analysis, translate stakeholder needs into production solutions, and manage analytics projects end-to-end while communicating results to technical and executive partners.
Top Skills: Machine LearningPythonRSalesforceServicenowSystem Log Analytics
16 Hours AgoSaved
Remote
Chicago, IL
190K-190K Annually
Senior level
190K-190K Annually
Senior level
Security • Cybersecurity
Design, build, and deploy production-grade ML systems for ICS/xOT cybersecurity, including threat detection, anomaly detection, NLP/LLM applications, and scalable data pipelines with observability and MLOps practices for cloud and on-prem environments.
Top Skills: Ci/CdDockerGoHuggingfaceJavaKubernetesLlmsMessage QueuingMlopsModel VersioningNlpPipeline OrchestrationPythonPyTorchRetrieval-Augmented Generation (Rag)RustScikit-LearnSQLStream ProcessingTensorFlow
Reposted 19 Hours AgoSaved
Remote or Hybrid
Chicago, IL
122K-160K Annually
Senior level
122K-160K Annually
Senior level
Edtech • Information Technology • Software
The Machine Learning Engineer develops production ML algorithms and recommendation systems, collaborates with teams, and optimizes user experiences.
Top Skills: DockerKubernetesNode.jsPythonTensorFlowTypescript
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Reposted 23 Days AgoSaved
Easy Apply
Remote
Chicago, IL
Easy Apply
200K-275K Annually
Senior level
200K-275K Annually
Senior level
Big Data • Fintech • Mobile • Payments • Financial Services
Manage a team of ML engineers to build and optimize Affirm's economic decisioning engine using advanced ML techniques. Collaborate across teams, provide technical leadership, and mentor engineers while driving a cohesive long-term ML strategy.
Top Skills: Agentic MlDeep LearningMachine LearningTransformersTree-Based Models
Reposted YesterdaySaved
Remote
Chicago, IL
175K-230K Annually
Senior level
175K-230K Annually
Senior level
Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Software • Generative AI
The Sr. Machine Learning Engineer will develop and deploy ML solutions for healthcare, manage data pipelines, and work with large datasets to enhance healthcare delivery.
Top Skills: AWSC++KubernetesPythonPyTorchScikit-LearnSparkTensorFlow
Reposted 2 Days AgoSaved
Remote
Chicago, IL
200K-240K Annually
Senior level
200K-240K Annually
Senior level
Fintech • Information Technology • Software
As a Staff Applied ML Scientist, you will develop and maintain fraud detection models, conduct research on fraud types, and collaborate across teams to drive product development and real-time decision-making.
Top Skills: AWSPostgresPython 3
Reposted 2 Days AgoSaved
Remote
Chicago, IL
200K-240K Annually
Senior level
200K-240K Annually
Senior level
Fintech • Information Technology • Software
As a Senior Applied ML Scientist, you'll develop fraud detection models, research new fraud types, and write production code while collaborating across teams to enhance SentiLink's identity verification solutions.
Top Skills: Aws Ec2Aws RdsAws RedshiftAws S3PostgresPython 3
Reposted 4 Days AgoSaved
Easy Apply
Remote or Hybrid
Chicago, IL
Easy Apply
179K-319K Annually
Senior level
179K-319K Annually
Senior level
Artificial Intelligence • Cloud • Computer Vision • Hardware • Internet of Things • Software
As a Staff Machine Learning Engineer, you will design AI products on Edge devices, optimize ML model performance, and work with large-scale datasets, collaborating across teams to deliver impactful solutions.
Top Skills: C++PythonRayRustSpark
Reposted 8 Days AgoSaved
In-Office or Remote
Chicago, IL
Senior level
Senior level
Big Data • Food • Mobile • Payments
The Senior Machine Learning Engineer leads technical direction for ML systems focused on personalization and ranking, overseeing architecture and implementation while mentoring team members.
Top Skills: Ai ToolsData PipelinesDistributed SystemsLlmsMachine LearningMl Infrastructure
52 Minutes AgoSaved
Remote
Chicago, IL
250K-285K Annually
Senior level
250K-285K Annually
Senior level
Retail
Lead end-to-end supply chain planning science: own forecasting tournaments, inventory placement optimization, vendor performance systems, and raw-material signals. Define methodology, production models, and iteration loops; drive AI-native workflows (LLM-aided EDA, agentic feature engineering), partner with planning operators and engineering, and mentor junior scientists to raise methodological standards and deliver measurable business impact.
Top Skills: Agentic LoopsAIExperimentationFeature PipelinesForecastingInventory Placement OptimizationLlmsMachine LearningModel ServingOperations ResearchTournament FrameworksVendor Performance Modeling
Reposted 2 Days AgoSaved
Remote
Chicago, IL
250K-300K Annually
Senior level
250K-300K Annually
Senior level
Automotive • Insurance • Machine Learning • Mobile • Software
Lead a multidisciplinary team to design, deploy, and optimize ML-driven bidding systems and measurement for a nine-figure marketing budget. Drive experimentation, partner strategy, media-mix optimization, and end-to-end measurement while aligning Marketing, Analytics, Engineering, and Product to improve marketing ROI and scale performance.
Top Skills: AWSMachine LearningMobile Telematics
Reposted 12 Days AgoSaved
In-Office
Chicago, IL
Senior level
Senior level
Manufacturing
Design, build, and deploy machine learning systems for controlling quantum processors. Develop reinforcement learning and Bayesian methods for QEC calibration, and work cross-functionally with product and R&D teams.
Top Skills: Deep LearningMachine LearningPythonReinforcement Learning
Reposted 8 Days AgoSaved
Remote or Hybrid
Chicago, IL
119K-201K Annually
Senior level
119K-201K Annually
Senior level
Artificial Intelligence • Cloud • Sales • Security • Software • Cybersecurity • Data Privacy
The Senior Machine Learning Engineer will design, implement, and optimize machine learning models, drive AI initiatives, and collaborate cross-functionally to enhance SailPoint's AI capabilities.
Top Skills: AirflowAWSCloudbeesDbtFeastGoJenkinsKafkaPythonPyTorchQlikScikit-LearnShell/BashSnowflakeSQLTableauTensorFlow
Reposted 9 Days AgoSaved
Easy Apply
Remote
Chicago, IL
Easy Apply
194K-228K Annually
Senior level
194K-228K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Lead ML feature strategy and engineering for fraud detection, owning end-to-end pipelines, validating features at scale, and translating analytics into production ML systems. Drive tooling and architecture decisions, mentor junior team members, partner cross-functionally with product and risk teams, and apply practitioner-level ML knowledge to detect and prevent account takeover and scam activity.
Top Skills: FeastFeature StoreGeminiGleanLibrechatPythonSparkSQLTecton
Reposted 4 Days AgoSaved
Remote
Chicago, IL
200K-246K Annually
Senior level
200K-246K Annually
Senior level
Fashion
Lead a team of machine learning engineers and data scientists to develop algorithms for personalized shopping, enhancing client engagement and driving growth through AI and data science.
Top Skills: AICloud-Based InfrastructureData SystemsMachine LearningPython
Reposted 14 Days AgoSaved
In-Office
Chicago, IL
137K-200K Annually
Senior level
137K-200K Annually
Senior level
Artificial Intelligence • Automotive • Internet of Things • Software
The Senior Manager for Machine Learning will lead the ML team, coordinate initiatives, and enhance product development in a collaborative environment.
Top Skills: AWSIamLambdaMachine LearningMlopsSagemakerStepfunctions
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