Top Senior Data Science Jobs in Chicago, IL

Reposted 6 Days AgoSaved
Remote
Chicago, IL
150K-195K Annually
Senior level
150K-195K Annually
Senior level
Software • Cryptocurrency • Web3
Partner with Marketing as the embedded data science lead to build marketing measurement, attribution, LTV/ROAS/CAC models, run experiments, analyze the full funnel, create forecasts and dashboards, and influence channel strategy and budget allocation.
Top Skills: Ad PlatformsAppsflyerGoogle AnalyticsLookerMmpPythonRSQLTableau
Reposted 6 Days AgoSaved
Remote
Chicago, IL
255K-298K Annually
Senior level
255K-298K Annually
Senior level
Consumer Web • Other • Social Media • Software
As the Staff Data Scientist, you will lead the data science function, driving strategy, mentoring peers, and shaping product direction through advanced analytics and experimentation.
Top Skills: PythonSQL
Reposted 7 Days AgoSaved
Remote
Chicago, IL
Senior level
Senior level
Big Data • Food • Mobile • Payments
Lead company-level measurement and causal strategy, define MAU×ARPU metrics and semantic mart, set scientific standards for experimentation and analysis, own strategic models (MMM, elasticity, forecasting), partner with engineering to productionize analytics, and raise org-wide scientific maturity through governance, templates, and upskilling.
Top Skills: DbtExperimentation PlatformsPythonSnowflakeSQL
Reposted 12 Days AgoSaved
Remote
Chicago, IL
160K-220K Annually
Senior level
160K-220K Annually
Senior level
Fintech • Financial Services
Lead and deliver end-to-end data science projects: design, build, deploy, and monitor ML/statistical models for credit risk, pricing, collections, and fraud. Partner with cross-functional teams to integrate models into production, set model development standards, mentor engineers, and maintain reliable ML pipelines and monitoring systems.
Top Skills: AWSGitPythonSagemakerSQL
Reposted 22 Days AgoSaved
Hybrid
Chicago, IL
100K-175K Annually
Senior level
100K-175K Annually
Senior level
Artificial Intelligence • Big Data • Healthtech • Machine Learning • Analytics • Biotech • Generative AI
This role involves onboarding clients, solving scientific problems, guiding data analysis on the Tempus platform, and creating documentation. Requires expertise in biomedical datasets and programming.
Top Skills: Ai-Assisted ToolsAWSDockerGCPGitGitLinuxPythonR
Reposted 9 Days AgoSaved
Remote
Chicago, IL
Senior level
Senior level
Machine Learning • Software
The Staff Data Scientist will lead the development and deployment of ML and GenAI systems to detect billing errors and fraud in healthcare payments, collaborating with cross-functional teams.
Top Skills: AIData ScienceMachine Learning
Reposted 11 Days AgoSaved
Remote
Chicago, IL
Senior level
Senior level
Cloud • Information Technology • Software • Consulting • Web3
Seeking a skilled Data Scientist/Machine Learning Engineer to develop machine learning models, design AI systems, and collaborate in data analytics. Responsibilities include productionizing models, data engineering, and cross-functional collaboration.
Top Skills: AirflowAWSAzureCi/CdDockerGCPJIRAKubeflowKubernetesMlflowNumpyPandasPlantumlPythonPyTorchSparkTfx
Reposted 12 Days AgoSaved
Remote
Chicago, IL
175K-234K Annually
Senior level
175K-234K Annually
Senior level
Information Technology • Other • Social Media
As a Senior Data Scientist, you'll optimize search relevance, retrieve content, analyze data, and collaborate with teams to enhance product strategies.
Top Skills: Ml ModelsNumpyPandasPythonScikit-LearnSQL
Reposted 22 Days AgoSaved
In-Office
Chicago, IL
196K-245K Annually
Senior level
196K-245K Annually
Senior level
Blockchain • Financial Services • Cryptocurrency • Web3 • Quantitative Trading
As a Staff Data Scientist, you will lead the Platform Data team in building a scalable data platform, collaborate on architecture and solutions, mentor team members, and drive improvements in technology and methodologies.
Top Skills: Aws Data ServicesAzure Paas ServicesC#/.NetData LakeDatabricksLakehousePostgresPowershellPythonQlikSQLSQL ServerZoho Analytics
Reposted 14 Hours AgoSaved
In-Office or Remote
Chicago, IL
Senior level
Senior level
Insurance
The Lead Data Scientist will develop advanced analytical solutions for pricing and customer insights in pet insurance, mentor teams, and collaborate with stakeholders.
Top Skills: DatabricksDbtPythonSnowflakeSQL
Reposted 14 Days AgoSaved
Remote
Chicago, IL
217K-289K Annually
Senior level
217K-289K Annually
Senior level
Internet of Things
Lead data-driven strategy by partnering with senior executives to deliver rigorous analytical solutions. Design and implement sophisticated analyses on large-scale data, build trusted cross-functional relationships, mentor data scientists, and influence long-term product and business decisions.
Top Skills: PythonRSQL
Reposted 20 Days AgoSaved
Remote
Chicago, IL
180K-230K Annually
Senior level
180K-230K Annually
Senior level
Fintech • Information Technology • Software
As a Senior Data Scientist, you'll develop fraud detection models, perform detailed analyses, and work closely with teams to drive product innovation and business outcomes.
Top Skills: Aws Ec2Aws RdsAws RedshiftAws S3PostgresPython 3
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Reposted 20 Days AgoSaved
Easy Apply
Remote
Chicago, IL
Easy Apply
160K-200K Annually
Senior level
160K-200K Annually
Senior level
Artificial Intelligence • Enterprise Web • Information Technology • Productivity • Sales • Software • Database
The Senior Data Scientist will analyze data to drive product strategy, optimize performance, and support product launches, collaborating with cross-functional teams.
Top Skills: A/B TestingAmplitudeHeapLookerMachine LearningMixpanelPythonRSASSQL
Reposted 16 Days AgoSaved
Remote
Chicago, IL
130K-168K Annually
Senior level
130K-168K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Lead a 5–8 person Data Science team to develop and operationalize FWA detection models using SAS and Python on multi‑payer healthcare claims. Oversee model development, data pipelines, quality reviews, stakeholder presentations, and collaboration with SMEs and BI developers. Split role ~40% management, 60% hands-on coding/analysis.
Top Skills: AWSCptDrgHcpcsIcd-10ExcelMicrosoft PowerpointMicrosoft WordPythonSASSnowflakeSQL
Reposted 4 Days AgoSaved
In-Office or Remote
Chicago, IL
143K-304K Annually
Senior level
143K-304K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Lead end-to-end data science for customer-embedded, production solutions: acquire and prepare messy datasets, develop and evaluate models tied to business outcomes, run experiments, deploy operational models at scale, coach cross-disciplinary teams, and drive strategy, ethics, and privacy discussions.
Reposted 18 Days AgoSaved
Remote
Chicago, IL
Senior level
Senior level
Machine Learning • Software
As a Staff Data Scientist, you will lead initiatives to build and optimize machine learning models, collaborate across departments, and solve complex business problems using data.
Top Skills: LlmMlSQL
Reposted 18 Days AgoSaved
Remote
Chicago, IL
140K-240K Annually
Senior level
140K-240K Annually
Senior level
Greentech
As a Data Scientist, you will build predictive models, develop software tools, and analyze geoscientific data to support mineral exploration and discovery.
Top Skills: Cicd PipelinesCloud ComputingCollaborative Software DevelopmentData Science PackagesGeospatial AnalysesGitMachine LearningPythonVisualizations
Reposted 18 Days AgoSaved
Remote
Chicago, IL
140K-240K Annually
Senior level
140K-240K Annually
Senior level
Greentech
As a Data Scientist, you will develop predictive models, analyze geoscientific data, and collaborate with geoscientists to improve mineral exploration efforts.
Top Skills: Cloud ComputingGeospatial AnalysisPythonSoftware Engineering
Reposted 5 Days AgoSaved
In-Office or Remote
Chicago, IL
120K-261K Annually
Senior level
120K-261K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Lead end-to-end data science projects: acquire and prepare messy datasets, develop and evaluate models tied to business outcomes, operationalize models at scale, run experiments, drive ethics/privacy, partner with customers and teams, and coach cross-disciplinary colleagues.
6 Days AgoSaved
In-Office
Chicago, IL
120K-200K Annually
Senior level
120K-200K Annually
Senior level
Fintech • Payments
Lead data science for fraud and risk analytics: translate business challenges into metrics, analytics, experimentation, and BI; build, productionize, and enhance models and decisioning frameworks; run statistical analysis and A/B tests; collaborate with product, finance, compliance and legal; communicate insights to senior leadership; and champion data quality and accessibility.
Top Skills: PythonSQLTableau
Reposted 6 Days AgoSaved
In-Office
Chicago, IL
131K-194K Annually
Senior level
131K-194K Annually
Senior level
Fintech • Payments
Lead development of data science models, mentor junior scientists, ensure data quality, and collaborate with stakeholders on requirements.
Top Skills: LookerPlotlyPower BIPythonSeabornSQLTableau
21 Days AgoSaved
In-Office or Remote
Chicago, IL
109K-181K Annually
Senior level
109K-181K Annually
Senior level
Healthtech • Information Technology • Software
Provide analytics and data-driven insights for CoverMyMeds clients, prioritize work that drives commercial outcomes, build relationships with account teams, apply statistical and predictive methods, monitor portfolio health, deliver client-facing visuals and recommendations, support complex requests and escalations, and inform strategic decisions across product, analytics, and operations.
Top Skills: ExcelMatlabPythonRSASSQLTableau
Reposted 21 Days AgoSaved
Remote
Chicago, IL
200K-242K Annually
Senior level
200K-242K Annually
Senior level
Real Estate • Travel • PropTech
Develop frameworks and tooling to estimate long-term impacts of product changes from short-term experiment outcomes. Build causal inference methods (experimental, econometric, quasi-experimental), evaluate heterogeneous treatment effects, own major estimation problems, and communicate results to technical and non-technical stakeholders to drive better long-term decisions.
Top Skills: C++JavaPythonRScala
Reposted 8 Days AgoSaved
In-Office
Chicago, IL
122K-228K Annually
Senior level
122K-228K Annually
Senior level
Financial Services
The Principal Data Scientist develops predictive models, designs large-scale data pipelines, and collaborates to enhance data-driven decision-making using advanced analytical algorithms.
Top Skills: Artificial IntelligenceAWSAzureDeep LearningGenaiLlmLstmMachine LearningMlopsPower BIPyTorchTensorFlowXgboosting
Reposted 22 Days AgoSaved
Remote
Chicago, IL
Senior level
Senior level
AdTech • Big Data • Consumer Web • Digital Media • Marketing Tech
Lead end-to-end data science for a priority vertical (Insurance), building, validating, and deploying ML models that drive ROAS and lead quality. Partner with stakeholders and ML engineering to monitor live performance, iterate models, and identify new modeling opportunities to improve revenue and media efficiency.
Top Skills: AWSLtv ModelingMulti-Armed BanditPythonRanking SystemsRecommendation SystemsReinforcement LearningSQL
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